Skip to main content
Funded Studies

Christian Johannes Gloeckner, PhD

Group Leader at German Center for Neurodegenerative Diseases (DZNE)

Location: Tubingen Germany

Dr. Christian Johannes Gloeckner studied biochemistry at the University of Hannover and at the Hannover Medical School and obtained his PhD from the Technical University of Munich in 2001. During his doctoral work, Dr. Gloeckner studied protein-protein interactions. As post-doctoral fellow (2001-2004) at LMU Munich, he developed methods to isolate and purify protein complexes associated with inherited diseases using mass spectrometry (specialized technique used to sort chemicals). During that time, he also worked with liquid chromatography tandem--mass spectrometry, another technique that is used to separate and study proteins. Later, at the Helmholtz Zentrum München (2004-2014) and at the University of Tübingen (2010-2014), Dr. Gloeckner studied the functional characterization of Parkinson's disease-associated protein LRRK2. He participated in several studies that evaluated the biochemistry and protein structure of LRRK2, in addition to its associated protein interaction networks and its protein. Based on this work, Dr. Gloeckner reported one of the first demonstrations of LRRK2 kinase activity (2006) and also put forth a structural model of LRRK2 (2016).


Associated Grants

  • Biochemical and Structural Characterization of LRRK2-specific Nanobodies

    2019


  • Development of Nanobodies as Novel Tools to Characterize LRRK2 as a Potential Drug Target for Parkinson's Disease

    2017


  • From Structure to Function: Targeting LRRK2-mediated Parkinson's Disease

    2017


  • Identification of Slow Off-rate Modified Aptamer Reagents that Specifically Bind Phosphorylated LRRK2

    2016


We use cookies to ensure that you get the best experience. By continuing to use this website, you indicate that you have read our Terms of Service and Privacy Policy.