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Fredric P. Manfredsson, PhD

Associate Professor at Barrow Neurological Institute

Location: Phoenix, AZ United States

Fredric Manfredsson received his undergraduate training in microbiology at Arizona State University in Tempe, AZ and his PhD in Biomedical Sciences-Neuroscience from the University of Florida. He then received postdoctoral training in the laboratories of Dr. Ronald Mandel and Dr. Alfred S. Lewin during which he focused on viral vector design and gene-therapy for neurodegenerative disorders. Dr. Manfredsson joined the neuroscience faculty at the University of Florida as a research assistant professor in 2010. In the end of 2010 he was hired as an assistant professor with the Department of Translational Science and Molecular Medicine at the new Michigan State University College of Human Medicine campus in Grand Rapids, MI.

Recently Dr. Manfredsson was hired as an associate professor of neurobiology at Barrow Neurological Institute. His research continues to focus on the application of viral vectors in the study of, and treatment of, motor and non-motor features of Parkinson’s disease.

Associated Grants

  • Targeting of the Raphe-Cortical Pathway to Reduce Levodopa-Induced Psychosis


  • URMC-099 in an In Vivo AAV-hSYN Model of Parkinson’s Disease


  • Alpha-synuclein Aggregation Leads to Loss of Functional Forms of the Protein and Toxicity


  • Alpha-Synuclein Knockdown: Therapeutic or Toxic?


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