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Funded Studies

J. Javier Bravo-Cordero, PhD

Assistant Professor at Icahn Medical School at Mount Sinai

Location: New York, NY United States

Dr. Bravo-Cordero was trained as a cell biologist and molecular biologist. As a graduate student at the Spanish National Cancer Institute in Madrid, he worked on mechanisms of tumor cell invasion in 3D collagen matrices using high-resolution confocal imaging. During his postdoc at the Albert Einstein College of Medicine he used FRET microscopy and intravital imaging in mice order to study spatiotemporal activation of RhoGTPases during invasive processes of tumor cells. His work defined new molecular pathways and spatiotemporal kinetics of RhoGTPase signaling at invadopodia. The work in his own lab at Mount Sinai is focused on understanding how tumor cells disseminate during metastasis. His studies are highly collaborative and allow him to study tumor cell invasion in different tumor types, including melanoma, from different angles. These studies have uncovered novel functions and pathways in tumor cell invasion instrumental in understanding the early stages of metastasis.


Associated Grants

  • LRRK2 Regulation of Melanoma Progression

    2021


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