Dr. Michael Henderson is a senior postdoctoral fellow at the Center for Neurodegenerative Disease Research at the University of Pennsylvania. He earned an undergraduate degree from Florida State University, where he researched the regulation of voltage-gated potassium channel Kv1.3. During his PhD studies at Yale University, he investigated synaptic protein folding and identified the primary pathological aggregate in rare cases of adult-onset neuronal ceroid lipofuscinosis. His postdoctoral work has focused on understanding cell signaling pathways underlying Parkinson’s disease pathogenesis and testing therapeutic molecules in pre-clinical models. He is now investigating how genetic risk factors can alter the cell-to-cell spread and toxicity of pathological proteins in the brain.