Dr. Sonia Gandhi is a Group Leader at The Francis Crick Institute and UCL (University College London) and a Consultant Neurologist at the National Hospital for Neurology & Neurosurgery. She undertook her undergraduate and postgraduate studies at the University of Cambridge and University of Oxford. She subsequently completed a PhD studying the role of PINK1 in Parkinson’s disease at UCL. In 2014, she established her laboratory at the UCL Institute of Neurology and was awarded a secondment to the Francis Crick Institute in 2017. Her laboratory develops human iPSC-based models of disease, and utilizes a range of biophysical and cellular approaches to understand how alpha-synuclein aggregation impacts cellular physiology. This has enabled the dissection of cellular mechanisms, in particular mitochondrial dysfunction, oxidative stress, calcium signaling and inflammation, that may lead to neuronal death in Parkinson's disease.