4751 - 4775 of 8808 Results
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OPENTitle: Brain-restricted mTOR inhibition with binary pharmacologyJournal Name: NaturePublisher: Springer Science and Business Media LLCVol: 609Issue #: 7928Start Page: 822End Page: 828Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41586-022-05213-yBest OA location URL: https://www.nature.com/articles/s41586-022-05213-y.pdfCitation Count: 60
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OPENTitle: New insights into the genetic etiology of Alzheimer’s disease and related dementiasJournal Name: Nature GeneticsPublisher: Springer Science and Business Media LLCVol: 54Issue #: 4Start Page: 412End Page: 436Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41588-022-01024-zBest OA location URL: https://www.nature.com/articles/s41588-022-01024-z.pdfCitation Count: 1694
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OPENTitle: EndoMAP.v1 charts the structural landscape of human early endosome complexesJournal Name: NaturePublisher: Springer Science and Business Media LLCVol: 643Issue #: 8070Start Page: 252End Page: 261Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41586-025-09059-yBest OA location URL: https://www.nature.com/articles/s41586-025-09059-y.pdfCitation Count: 0
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RESTRICTEDTitle: VAMP2 chaperones α-synuclein in synaptic vesicle co-condensatesJournal Name: Nature Cell BiologyPublisher: Springer Science and Business Media LLCVol: 26Issue #: 8Start Page: 1287End Page: 1295Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1038/s41556-024-01456-1Citation Count: 23
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OPENTitle: Structure of LRRK2 in Parkinson’s disease and model for microtubule interactionJournal Name: NaturePublisher: Springer Science and Business Media LLCVol: 588Issue #: 7837Start Page: 344End Page: 349Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/s41586-020-2673-2Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7726071Citation Count: 203
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OPENTitle: Use of Glycolysis‐Enhancing Drugs and Risk of Parkinson's DiseaseJournal Name: Movement DisordersPublisher: WileyVol: 37Issue #: 11Start Page: 2210End Page: 2216Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1002/mds.29184Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.29184Citation Count: 23
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OPENTitle: JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degenerationJournal Name: Journal of NeurochemistryPublisher: WileyVol: 107Issue #: 6Start Page: 1578End Page: 1588Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1471-4159.2008.05713.xBest OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1471-4159.2008.05713.x?download=trueCitation Count: 79
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OPENTitle: UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicalsJournal Name: NaturePublisher: Springer Science and Business Media LLCVol: 454Issue #: 7206Start Page: 846End Page: 851Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nature07181Best OA location URL: http://doi.org/10.1038/nature07181Citation Count: 685
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OPENTitle: Deficiency of the frontotemporal dementia gene GRN results in gangliosidosisJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 13Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41467-022-33500-9Best OA location URL: https://www.nature.com/articles/s41467-022-33500-9.pdfCitation Count: 73
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OPENTitle: A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer’s diseaseJournal Name: Nature MedicinePublisher: Springer Science and Business Media LLCVol: 31Issue #: 5Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-nd, cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/s41591-025-03565-2Best OA location URL: https://www.nature.com/articles/s41591-025-03565-2.pdfCitation Count: 19
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OPENTitle: Association of vitamin K with cognitive decline and neuropathology in community‐dwelling older personsJournal Name: Alzheimer's & Dementia: Translational Research & Clinical InterventionsPublisher: WileyVol: 8Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-nd, cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/trc2.12255Best OA location URL: https://doi.org/10.1002/trc2.12255Citation Count: 42
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OPENTitle: The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damageJournal Name: Nature Cell BiologyPublisher: Springer Science and Business Media LLCVol: 27Issue #: 5Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41556-025-01653-6Best OA location URL: https://www.nature.com/articles/s41556-025-01653-6.pdfCitation Count: 1
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OPENTitle: Dopamine neuron activity encodes the length of upcoming contralateral movement sequencesJournal Name: Current BiologyPublisher: Elsevier BVVol: 34Issue #: 5Start Page: 1034End Page: 1047.e4Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.cub.2024.01.067Best OA location URL: http://www.cell.com/article/S0960982224001040/pdfCitation Count: 6
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OPENTitle: Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learningJournal Name: Cell SystemsPublisher: Elsevier BVVol: 15Issue #: 5Start Page: 475End Page: 482.e6Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.cels.2024.04.006Best OA location URL: http://www.cell.com/article/S2405471224001212/pdfCitation Count: 9
- Haploinsufficiency of ITSN1 is associated with a substantial increased risk of Parkinson’s disease2025OPENTitle: Haploinsufficiency of ITSN1 is associated with a substantial increased risk of Parkinson’s diseaseJournal Name: Cell ReportsPublisher: Elsevier BVVol: 44Issue #: 3Start Page: 115355End Page: 115355Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.celrep.2025.115355Best OA location URL: https://www.cell.com/action/showPdf?pii=S2211124725001263Citation Count: 2
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OPENTitle: Genetic variants and functional pathways associated with resilience to Alzheimer’s diseaseJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 143Issue #: 8Start Page: 2561End Page: 2575Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc, cc-by-ncDOI - Digital Object Identifier: 10.1093/brain/awaa209Best OA location URL: https://academic.oup.com/brain/article-pdf/143/8/2561/37356057/awaa209.pdfCitation Count: 126
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OPENTitle: In situ architecture of the lipid transport protein VPS13C at ER–lysosome membrane contactsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 119Issue #: 29Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1073/pnas.2203769119Best OA location URL: https://doi.org/10.1073/pnas.2203769119Citation Count: 62
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OPENTitle: Triglycerides are an important fuel reserve for synapse function in the brainJournal Name: Nature MetabolismPublisher: Springer Science and Business Media LLCVol: 7Issue #: 7Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s42255-025-01321-xBest OA location URL: https://www.nature.com/articles/s42255-025-01321-x.pdfCitation Count: 0
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OPENTitle: Intra-striatal AAV2.retro administration leads to extensive retrograde transport in the rhesus macaque brain: implications for disease modeling and therapeutic developmentJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41598-020-63559-7Best OA location URL: https://www.nature.com/articles/s41598-020-63559-7.pdfCitation Count: 60
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OPENTitle: Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9Journal Name: NeuronPublisher: Elsevier BVVol: 110Issue #: 5Start Page: 824End Page: 840.e10Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-nd, cc-by-nc-nd, cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.neuron.2021.12.031Best OA location URL: http://www.cell.com/article/S089662732101076X/pdfCitation Count: 81
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OPENTitle: Targeted micro-fiber arrays for measuring and manipulating localized multi-scale neural dynamics over large, deep brain volumes during behaviorJournal Name: NeuronPublisher: Elsevier BVVol: 112Issue #: 6Start Page: 909End Page: 923.e9Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.neuron.2023.12.011Best OA location URL: http://www.cell.com/article/S0896627323009704/pdfCitation Count: 14
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OPENTitle: TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse modelsJournal Name: Nature NeurosciencePublisher: Springer Science and Business Media LLCVol: 27Issue #: 5Start Page: 873End Page: 885Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/s41593-024-01610-wBest OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/11102654Citation Count: 23
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OPENTitle: Blood transcriptomic signatures associated with molecular changes in the brain and clinical outcomes in Parkinson’s diseaseJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 14Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41467-023-39652-6Best OA location URL: https://www.nature.com/articles/s41467-023-39652-6.pdfCitation Count: 28
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OPENTitle: Positive Reinforcement Mediated by Midbrain Dopamine Neurons Requires D1 and D2 Receptor Activation in the Nucleus AccumbensJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 9Issue #: 4Start Page: e94771End Page: e94771Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0094771Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094771&type=printableCitation Count: 146
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OPENTitle: Identifying and characterising sources of variability in digital outcome measures in Parkinson’s diseaseJournal Name: npj Digital MedicinePublisher: Springer Science and Business Media LLCVol: 5Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41746-022-00643-4Best OA location URL: https://www.nature.com/articles/s41746-022-00643-4.pdfCitation Count: 18