7251 - 7300 of 8436 Results
Title
Year
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OPENTitle: Dual κ‐agonist/μ‐antagonist opioid receptor modulation reduces levodopa‐induced dyskinesia and corrects dysregulated striatal changes in the nonhuman primate model of Parkinson diseaseJournal Name: Annals of NeurologyPublisher: WileyVol: 77Issue #: 6Start Page: 930End Page: 941Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.24375Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ana.24375Citation Count: 49
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OPENTitle: ER proteostasis disturbances in Parkinson's disease: novel insightsJournal Name: Frontiers in Aging NeurosciencePublisher: Frontiers Media SAVol: 7Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnagi.2015.00039Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnagi.2015.00039/pdfCitation Count: 31
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OPENTitle: Selective loss of glucocerebrosidase activity in sporadic Parkinson’s disease and dementia with Lewy bodiesJournal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13024-015-0010-2Best OA location URL: https://molecularneurodegeneration.biomedcentral.com/counter/pdf/10.1186/s13024-015-0010-2Citation Count: 137
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OPENTitle: Genetic analysis of FMR1 repeat expansion in essential tremorJournal Name: Neuroscience LettersPublisher: Elsevier BVVol: 593Issue #:Start Page: 114End Page: 117Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neulet.2015.03.027Best OA location URL: https://europepmc.org/articles/pmc4393799?pdf=renderCitation Count: 13
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OPENTitle: Stiripentol for the treatment of super-refractory status epilepticusJournal Name: Acta Neurologica ScandinavicaPublisher: WileyVol: 132Issue #: 6Start Page: 435End Page: 439Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/ane.12403Best OA location URL: https://doi.org/10.1111/ane.12403Citation Count: 41
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RESTRICTEDTitle: A visual review of the interactome of LRRK2: Using deep‐curated molecular interaction data to represent biologyJournal Name: PROTEOMICSPublisher: WileyVol: 15Issue #: 8Start Page: 1390End Page: 1404Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-byDOI - Digital Object Identifier: 10.1002/pmic.201400390Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pmic.201400390Citation Count: 38
- Nonmotor symptoms in healthy Ashkenazi Jewish carriers of the G2019S mutation in the LRRK2 gene2015OPENTitle: Nonmotor symptoms in healthy Ashkenazi Jewish carriers of the G2019S mutation in the LRRK2 geneJournal Name: Movement DisordersPublisher: WileyVol: 30Issue #: 7Start Page: 981End Page: 986Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26213Best OA location URL: https://europepmc.org/articles/pmc4478229?pdf=renderCitation Count: 60
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OPENTitle: Predicting the risk of mild cognitive impairment in the Mayo Clinic Study of AgingJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 84Issue #: 14Start Page: 1433End Page: 1442Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000001437Best OA location URL: https://europepmc.org/articles/pmc4395890?pdf=renderCitation Count: 123
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OPENTitle: Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophyJournal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13024-015-0008-9Best OA location URL: https://molecularneurodegeneration.biomedcentral.com/counter/pdf/10.1186/s13024-015-0008-9Citation Count: 142
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OPENTitle: Low‐variance RNAs identify Parkinson's disease molecular signature in bloodJournal Name: Movement DisordersPublisher: WileyVol: 30Issue #: 6Start Page: 813End Page: 821Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26205Best OA location URL: https://europepmc.org/articles/pmc4439364?pdf=renderCitation Count: 18
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OPENTitle: Similar striatal D2/D3 dopamine receptor availability in adults with Tourette syndrome compared with healthy controls: A [11C]‐(+)‐PHNO and [11C]raclopride positron emission tomography imaging studyJournal Name: Human Brain MappingPublisher: WileyVol: 36Issue #: 7Start Page: 2592End Page: 2601Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/hbm.22793Best OA location URL: https://europepmc.org/articles/pmc6869505?pdf=renderCitation Count: 19
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OPENTitle: Constructing de Novo H2O2 Signaling via Induced Protein ProximityJournal Name: ACS Chemical BiologyPublisher: American Chemical Society (ACS)Vol: 10Issue #: 6Start Page: 1404End Page: 1410Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/acschembio.5b00170Best OA location URL: https://europepmc.org/articles/pmc4849873?pdf=renderCitation Count: 16
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OPENTitle: Extracellular vesicle sorting of α-Synuclein is regulated by sumoylationJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 129Issue #: 5Start Page: 695End Page: 713Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s00401-015-1408-1Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00401-015-1408-1.pdfCitation Count: 154
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RESTRICTEDTitle: Elucidating the Role of Site-Specific Nitration of α-Synuclein in the Pathogenesis of Parkinson’s Disease via Protein Semisynthesis and MutagenesisJournal Name: Journal of the American Chemical SocietyPublisher: American Chemical Society (ACS)Vol: 137Issue #: 15Start Page: 5041End Page: 5052Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1021/ja5131726Citation Count: 148
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OPENTitle: Structural alterations of the intestinal epithelial barrier in Parkinson’s diseaseJournal Name: Acta Neuropathologica CommunicationsPublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s40478-015-0196-0Best OA location URL: https://actaneurocomms.biomedcentral.com/counter/pdf/10.1186/s40478-015-0196-0Citation Count: 251
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OPENTitle: Detecting and monitoring the symptoms of Parkinson's disease using smartphones: A pilot studyJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 21Issue #: 6Start Page: 650End Page: 653Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2015.02.026Best OA location URL: https://publications.aston.ac.uk/id/eprint/25868/1/Detecting_and_monitoring_the_symptoms_of_Parkinson_s_disease_using_smartphones.pdfCitation Count: 351
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OPENTitle: Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 30Issue #: 7Start Page: 919End Page: 927Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26170Best OA location URL: http://doi.org/10.1002/mds.26170Citation Count: 275
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RESTRICTEDTitle: Differential effects of severe vs mild GBA mutations on Parkinson diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 84Issue #: 9Start Page: 880End Page: 887Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000001315Best OA location URL: https://europepmc.org/articles/pmc4351661?pdf=renderCitation Count: 282
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OPENTitle: Sarcopenia and impairment in cognitive and physical performanceJournal Name: Clinical Interventions in AgingPublisher: Informa UK LimitedVol:Issue #:Start Page: 663End Page: 663Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.2147/cia.s76275Best OA location URL: https://www.dovepress.com/getfile.php?fileID=24358Citation Count: 94
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RESTRICTEDTitle: Pharmacogenetics of Antipsychotic-Induced Movement Disorders as a Resource for Better Understanding Parkinson’s Disease Modifier GenesJournal Name: Frontiers in NeurologyPublisher: Frontiers Media SAVol: 6Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-byDOI - Digital Object Identifier: 10.3389/fneur.2015.00027Best OA location URL: https://www.frontiersin.org/articles/10.3389/fneur.2015.00027/pdfCitation Count: 7
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OPENTitle: Computational analysis of the LRRK2 interactomeJournal Name: PeerJPublisher: PeerJVol: 3Issue #:Start Page: e778End Page: e778Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.7717/peerj.778Best OA location URL: https://doi.org/10.7717/peerj.778Citation Count: 56
- Protection from cyanide‐induced brain injury by the Nrf2 transcriptional activator carnosic acid2015OPENTitle: Protection from cyanide‐induced brain injury by the Nrf2 transcriptional activator carnosic acidJournal Name: Journal of NeurochemistryPublisher: WileyVol: 133Issue #: 6Start Page: 898End Page: 908Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/jnc.13074Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.13074Citation Count: 57
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OPENTitle: Can Parkinson’s disease be cured by stimulating neurogenesis?Journal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 125Issue #: 3Start Page: 978End Page: 980Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1172/jci80822Best OA location URL: http://www.jci.org/articles/view/80822/files/pdfCitation Count: 10
- Chemogenomic Profiling of Endogenous PARK2 Expression Using a Genome-Edited Coincidence Reporter2015OPENTitle: Chemogenomic Profiling of Endogenous PARK2 Expression Using a Genome-Edited Coincidence ReporterJournal Name: ACS Chemical BiologyPublisher: American Chemical Society (ACS)Vol: 10Issue #: 5Start Page: 1188End Page: 1197Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/cb5010417Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927027Citation Count: 54
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RESTRICTEDTitle: Molecular imaging of levodopa-induced dyskinesiasJournal Name: Cellular and Molecular Life SciencesPublisher: Springer Science and Business Media LLCVol: 72Issue #: 11Start Page: 2107End Page: 2117Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1007/s00018-015-1854-xCitation Count: 17
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OPENTitle: Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer’s diseaseJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 129Issue #: 4Start Page: 565End Page: 583Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s00401-015-1395-2Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00401-015-1395-2.pdfCitation Count: 47
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OPENTitle: Novel Antioxidants Protect Mitochondria from the Effects of Oligomeric Amyloid Beta and Contribute to the Maintenance of Epigenome FunctionJournal Name: ACS Chemical NeurosciencePublisher: American Chemical Society (ACS)Vol: 6Issue #: 4Start Page: 588End Page: 598Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/cn500323qBest OA location URL: https://europepmc.org/articles/pmc4838453?pdf=renderCitation Count: 11
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OPENTitle: Alpha1-chimaerin, a Rac1 GTPase-activating protein, is expressed at reduced mRNA levels in the brain of Alzheimer’s disease patientsJournal Name: Neuroscience LettersPublisher: Elsevier BVVol: 591Issue #:Start Page: 19End Page: 24Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neulet.2015.02.013Best OA location URL: https://europepmc.org/articles/pmc4382517?pdf=renderCitation Count: 11
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RESTRICTEDTitle: Cell penetrating peptide-mediated transport enables the regulated secretion of accumulated cargoes from mast cellsJournal Name: Journal of Controlled ReleasePublisher: Elsevier BVVol: 202Issue #:Start Page: 108End Page: 117Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.jconrel.2015.02.005Citation Count: 19
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OPENTitle: Identification of Synaptosomal Proteins Binding to Monomeric and Oligomeric α-SynucleinJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 10Issue #: 2Start Page: e0116473End Page: e0116473Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0116473Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0116473&type=printableCitation Count: 68
- Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson’s disease: a dose-finding study2015OPENTitle: Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson’s disease: a dose-finding studyJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 138Issue #: 4Start Page: 963End Page: 973Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1093/brain/awu409Best OA location URL: https://academic.oup.com/brain/article-pdf/138/4/963/13798742/awu409.pdfCitation Count: 151
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RESTRICTEDTitle: Effect of selective LRRK2 kinase inhibition on nonhuman primate lungJournal Name: Science Translational MedicinePublisher: American Association for the Advancement of Science (AAAS)Vol: 7Issue #: 273Start Page:End Page:Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1126/scitranslmed.aaa3634Citation Count: 331
- Enhanced histamine H2 excitation of striatal cholinergic interneurons in l-DOPA-induced dyskinesia2015OPENTitle: Enhanced histamine H2 excitation of striatal cholinergic interneurons in l-DOPA-induced dyskinesiaJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 76Issue #:Start Page: 67End Page: 76Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nbd.2015.01.003Best OA location URL: https://doi.org/10.1016/j.nbd.2015.01.003Citation Count: 43
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RESTRICTEDTitle: Current Concepts in the Treatment of Multiple System AtrophyJournal Name: Movement Disorders Clinical PracticePublisher: WileyVol: 2Issue #: 1Start Page: 6End Page: 16Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mdc3.12145Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.12145Citation Count: 24
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RESTRICTEDTitle: Chemical methods for the proteome-wide identification of posttranslationally modified proteinsJournal Name: Current Opinion in Chemical BiologyPublisher: Elsevier BVVol: 24Issue #:Start Page: 27End Page: 37Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.cbpa.2014.10.020Best OA location URL: https://europepmc.org/articles/pmc4308425?pdf=renderCitation Count: 59
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RESTRICTEDTitle: Gaucher-related synucleinopathies: The examination of sporadic neurodegeneration from a rare (disease) angleJournal Name: Progress in NeurobiologyPublisher: Elsevier BVVol: 125Issue #:Start Page: 47End Page: 62Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.pneurobio.2014.12.001Best OA location URL: https://doi.org/10.1016/j.pneurobio.2014.12.001Citation Count: 65
- Plasma near-infrared spectroscopy for diagnosis of idiopathic Parkinson's disease: the SPIN-PD study2015RESTRICTEDTitle: Plasma near-infrared spectroscopy for diagnosis of idiopathic Parkinson's disease: the SPIN-PD studyJournal Name: Biomarkers in MedicinePublisher: Informa UK LimitedVol: 9Issue #: 2Start Page: 89End Page: 97Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.2217/bmm.14.103Citation Count: 5
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OPENTitle: Phosphorylated α-synuclein in Parkinson’s disease: correlation depends on disease severityJournal Name: Acta Neuropathologica CommunicationsPublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s40478-015-0185-3Best OA location URL: https://actaneurocomms.biomedcentral.com/counter/pdf/10.1186/s40478-015-0185-3Citation Count: 82
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OPENTitle: Placebo effect of medication cost in Parkinson diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 84Issue #: 8Start Page: 794End Page: 802Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000001282Best OA location URL: https://europepmc.org/articles/pmc4345649?pdf=renderCitation Count: 129
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OPENTitle: Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation ProgramJournal Name: NeuropathologyPublisher: WileyVol: 35Issue #: 4Start Page: 354End Page: 389Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/neup.12189Best OA location URL: https://europepmc.org/articles/pmc4593391?pdf=renderCitation Count: 410
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RESTRICTEDTitle: Leucine‐rich repeat kinase 2‐sensitive Na+/Ca2+exchanger activity in dendritic cellsJournal Name: The FASEB JournalPublisher: WileyVol: 29Issue #: 5Start Page: 1701End Page: 1710Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1096/fj.14-264028Citation Count: 19
- Management of impulse control disorders in Parkinson's disease: Controversies and future approaches2015RESTRICTEDTitle: Management of impulse control disorders in Parkinson's disease: Controversies and future approachesJournal Name: Movement DisordersPublisher: WileyVol: 30Issue #: 2Start Page: 150End Page: 159Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.26099Best OA location URL: https://europepmc.org/articles/pmc5077247?pdf=renderCitation Count: 92
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RESTRICTEDTitle: Extent of Inhibition of α-Synuclein Aggregation in Vitro by SUMOylation Is Conjugation Site- and SUMO Isoform-SelectiveJournal Name: BiochemistryPublisher: American Chemical Society (ACS)Vol: 54Issue #: 4Start Page: 959End Page: 961Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1021/bi501512mCitation Count: 56
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OPENTitle: Inducible nitric oxide synthase gene methylation and parkinsonism in manganese-exposed weldersJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 21Issue #: 4Start Page: 355End Page: 360Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2015.01.007Best OA location URL: https://europepmc.org/articles/pmc4512640?pdf=renderCitation Count: 34
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OPENTitle: Quantitative comparison of 21 protocols for labeling hippocampal subfields and parahippocampal subregions in in vivo MRI: Towards a harmonized segmentation protocolJournal Name: NeuroImagePublisher: Elsevier BVVol: 111Issue #:Start Page: 526End Page: 541Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neuroimage.2015.01.004Best OA location URL: https://europepmc.org/articles/pmc4387011?pdf=renderCitation Count: 332
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RESTRICTEDTitle: Neurodegeneration with Brain Iron Accumulation: Diagnosis and ManagementJournal Name: Journal of Movement DisordersPublisher: The Korean Movement Disorder SocietyVol: 8Issue #: 1Start Page: 1End Page: 13Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-by-ncDOI - Digital Object Identifier: 10.14802/jmd.14034Best OA location URL: https://doi.org/10.14802/jmd.14034Citation Count: 172
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OPENTitle: Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanismJournal Name: Journal of NeuroinflammationPublisher: Springer Science and Business Media LLCVol: 12Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s12974-014-0228-xBest OA location URL: https://jneuroinflammation.biomedcentral.com/counter/pdf/10.1186/s12974-014-0228-xCitation Count: 51
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OPENTitle: STEP 61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 112Issue #: 4Start Page: 1202End Page: 1207Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1417423112Best OA location URL: https://www.pnas.org/content/pnas/112/4/1202.full.pdfCitation Count: 58
- Regional cerebellar volumes are related to early musical training and finger tapping performance2015RESTRICTEDTitle: Regional cerebellar volumes are related to early musical training and finger tapping performanceJournal Name: NeuroImagePublisher: Elsevier BVVol: 109Issue #:Start Page: 130End Page: 139Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.neuroimage.2014.12.076Citation Count: 80
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OPENTitle: Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tauJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 125Issue #: 2Start Page: 681End Page: 686Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1172/jci78421Best OA location URL: http://www.jci.org/articles/view/78421/files/pdfCitation Count: 193