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Encouraging Early Results from Gene Therapy to Enhance Levodopa Response
December 8, 2016
… needed and the clinical effects of the treatment, but the early data is promising. Levodopa Limitations and Gene … The brain uses the enzyme AADC to convert levodopa into dopamine, the chemical messenger that helps control … the treatment. With imaging tools (MRI and PET scans), the researchers could see good results in getting the drug to …
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New Study Reveals Potential Biomarkers for Cognitive Changes in Early Parkinson's
May 17, 2017
… significantly. ( Read more about cognitive changes in PD. ) Researchers and doctors are currently unable to definitively … (objective measures) of cognitive changes and decline in early Parkinson's disease. The investigators, led by Daniel … and longer-term studies, but they give us a window into how and why cognitive problems develop in PD, and who …
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PPMI: Fall Parkinson’s Research Conference Highlights
November 7, 2024
… poised to shape the future of Parkinson’s disease research and community. From the International Congress of … as a research framework. Concordance of Neuropathologic Diagnosis of Lewy Body Disease with Baseline Alpha-Synuclein … tests as a simpler, non-invasive alternative to PSG for early diagnosis of neurodegenerative diseases like …
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Measurement of Mitochondrial DNA in Early Stages of Parkinson’s Disease
… this disorder first appears. Therefore, iRBD represents an early stage of PD that offers a unique opportunity for … in mitochondrial DNA bring about neurodegeneration early in PD. In this study, we seek to establish whether … or is a consequence of, Parkinson’s disease. Impact on Diagnosis/Treatment of Parkinson’s Disease: The proposed …
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Actor Alan Alda Reveals His Parkinson's Diagnosis: 'It's like a puzzle to be solved'
July 31, 2018
… Alda also discussed his initial reaction to a Parkinson's diagnosis and how he views his disease: "I was mainly … Morning . For more information on navigating a Parkinson's diagnosis, download Parkinson's 360 -- a toolkit developed …
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Transplanation of Cell-Derived Dopaminergic Neurons Into the Brains of MPTP-treated Pre-clinical Models
… that can induce mouse and primate ES cells to differentiate into mid/hindbrain neurons, dopaminergic (DA) neurons in … pre-clinical model ES cells have been transplanted into the brains of MPTP-treated pre-clinical models of … and to prove the effectiveness and safety of grafting them into the brains of MPTP-treated pre-clinical models. …