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Preclinical Screening of Compounds that Modulate the Pathological Interplay between Alpha-synuclein and Synapsin III for the Treatment of Parkinson’s Disease
… use preclinical models of PD, including organoids grown from cells derived from people with PD, to assess the pharmacological profile …
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Studying How Defects in Autophagy Contribute to the Aggregation of Alpha-synuclein in Neurons with LRRK2 Mutations
… the buildup of toxic protein clumps. Comparing the results from mouse and human neurons will allow us to test the … are consistent, we will investigate whether neurons from people with forms of PD that do not involve LRRK2 have …
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Identifying a Molecular Signature of DNA Damage in the Blood Cells of People with Parkinson’s Disease
… Study Design: We will analyze a large set of data obtained from blood samples available to The Michael J. Fox … studies in biological systems, such as neurons derived from people with PD or preclinical PD models, to further …
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Ask Us Anything: Answers to Your Questions about Gut Health and Parkinson’s (Webinar Audio)
November 1, 2023
… but less talked-about symptoms of PD. In this audio from our Third Thursdays Webinar, experts and people with PD … of this podcast. For more information, read a guest blog from panelist Wael El-Nachef, MD, PhD, on gastrointestinal …
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Episode 3: New Frontiers in Deep Brain Stimulation Research for Parkinson’s Disease with Dr. Michael Okun
November 21, 2023
… in deep brain stimulation and other areas. He draws from his extensive research and clinical experience applying … to The Michael J. Fox Foundation Parkinson’s Podcast. Hear from scientists, doctors and people with Parkinson's on …
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Xeomin (incobotulinumtoxinA)
… limit social interactions and irritate skin. Xeomin is made from the bacteria that causes botulism (an infectious … for Parkinson's Research has a policy of refraining from advocating, endorsing or promoting any drug therapy, …