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Michael J. Fox Foundation Awards Follow-on Grant to Envoy Therapeutics
May 9, 2012
… whether these compounds have the potential to limit dyskinesia, the debilitating, uncontrollable movements that …
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The Sherer Report: April 2012
April 19, 2012
… time, and are marked by significant side effects such as dyskinesia (uncontrollable and debilitating movement). The … a promising drug that targets serotonin as a treatment for dyskinesia. The trial is nearing completion and results are … of current formulations are also thought to contribute to dyskinesia. A more consistent delivery of levodopa could …
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Deep Brain Stimulation: a “Life-changing Decision”
December 5, 2013
… getting some relief for his Parkinson’s disease. But severe dyskinesia resulted, essentially “ruling his life.” Stark … help for those struggling with the motor symptoms of PD and dyskinesia. So he asked his physician about the procedure … have developed motor complications, such as wearing-off or dyskinesia; Do not have an unstable psychiatric condition; …
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The State of Science in Parkinson's Research
November 17, 2011
… existing therapies, limiting side effects such as dyskinesias, the uncontrollable movements that are a common … of levodopa without triggering adverse effects such as dyskinesias. Addex is studying how limiting the activity of … glutamate receptor called mGluR5 could reduce these dyskinesias. Significant evidence also exists to support the …
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Participating in a Clinical Trial is 'Easier than You Think,' Says One Volunteer
September 5, 2013
… trial Deb participated in tested a certain drug’s effect on dyskinesia, which is the difficulty or distortion in … the study, they decided she wasn’t a good candidate as her dyskinesia makes it difficult for her to stay still during …
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Research Recap: Highlights from the American Academy of Neurology Meeting
May 3, 2017
… levodopa is not working as well) or side effects such as dyskinesia (involuntary movements). Y-AADC01 was designed to avoid "off" episodes and dyskinesia by increasing ADCC, a chemical that converts …