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Does serum urate change as Parkinson's progresses
July 13, 2020
… Myolex, and his institution received grants on his behalf from Amylyx Pharmaceuticals, GlaxoSmithKline, and Mitsubishi …
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Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes
March 24, 2021
… was consistent across an overexpression model, neurons from a G2019S knockin mouse, and human induced pluripotent …
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Parkinson’s Pillow Talk: An Open Conversation on Sex, Sleep and Intimacy
February 16, 2022
… closer look at Parkinson’s in the bedroom — covering topics from sleep to mood changes and their impact on sex and …
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Use of Integrated, Multi-omic Data Analysis for Screening and Treatment of Parkinson’s Disease
… evolution and treatment response. Study Design: Using data from PD populations and prodromal individuals who have just …
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The AKT modulator A-443654 reduces α-synuclein expression and normalizes ER stress and autophagy
September 11, 2021
… Accumulation of α-synuclein is a main underlying pathological feature of Parkinson's disease and α-synucleinopathies, for which lowering expression of the α-synuclein gene (SNCA) is a potential therapeutic avenue. Using a cell-based luciferase reporter of …
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Michael J. Fox to Receive Oscar Statuette, the Jean Hersholt Humanitarian Award
June 22, 2022
… Awards on Saturday, November 19, 2022 in Los Angeles. From the official news release: “Michael J. Fox’s tireless …