The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2011Assessing the Therapeutic Potential of iDA Neuronal Cells in Autologous Strategy
Objective/Rationale:
We have shown recently that three transcription factors can promote the conversion of skin fibroblasts into induced dopaminergic neuronal (iDAN) cells with remarkable functional... -
Target Validation, 2011Targeting Beta-arrestin Signaling in the Treatment of Parkinson's Disease
Objective/Rationale:
Beta-arrestins were originally identified as proteins that attenuate the signaling function of the large class of receptors to which dopamine receptors belong. However, recently... -
Defining Cognitive Phenotypes of Parkinson's Disease, 2011Cognitive Phenotypes in Parkinson's Disease: Anatomical and Functional Correlates
Objective/Rationale:
Cognitive impairment with and without dementia is frequent in Parkinson's disease (PD). However, there is a high heterogeneity in the clinical presentation of these cognitive... -
Defining Cognitive Phenotypes of Parkinson’s Disease, 2011Bioanatomical Phenotype of Parkinson's Disease With and Without Cognitive Impairment
Objective/Rationale:
Mild cognitive impairment (MCI) and dementia are common in Parkinson’s disease. However, presently, it is difficult to recognize which aspects of cognitive changes are... -
Improving Levodopa Delivery, 2011Continuous Subcutaneous Levodopa Prodrug Infusion
Objective/Rationale:
Numerous studies demonstrate that continuous levodopa infusion can result in reductions of more than 50 percent in time spent in the "off" state and time spent with severe... -
Target Validation, 2011Caspase-8 Control Microglia Activation and Neurotoxicity in Parkinson's Disease
Objective/Rationale:
Sustained microglia activation and resulting neuroinflammation is believed to play an important role in the mechanism of chronic dopaminergic neuronal loss in Parkinson’s disease...
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Our funding programs support basic, translational and clinical research from academia and industry.