The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2008Can the electrocardiogram be used to identify pre-motor Parkinson's Disease
Objective/Rationale:
Loss of cardiac autonomic innervation is a near universal feature in Parkinson’s disease. In this proposal, we will determine if this feature of PD occurs before motor symptoms... -
Rapid Response Innovation Awards, 2008A Randomized, Double-Blind, Trial of Nexalin® vs. Placebo in Subjects with Early Parkinson's Disease
Objective/Rationale:
While the oral medications to treat PD are often quite effective in treating the physical symptoms (motor symptoms) such as tremor and stiffness, they may be associated with side... -
Rapid Response Innovation Awards, 2008Generation of a dorsal motor nucleus X (DMX) specific pre-clinical model of alpha synuclein overexpression to study the etiology of autonomic dysfunction in PD
Objective/Rationale:
The etiology for the non-motor symptoms in PD, such as autonomic instability, sleep disturbance, and constipation, remain poorly understood. In their recent studies of PD... -
MJFF Research Grant, 2008GDNF Fusion Protein for Blood-Brain Barrier Delivery and Treatment in Parkinson's Disease
Objective/Rationale:
GDNF is a naturally occurring protein in the brain that protects and rescues the part of the brain that degenerates in Parkinson’s disease (PD). However, GDNF does not cross the...
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MJFF Research Grant, 2008The anatomic basis of cardiac and cognitive changes in Parkinson's disease: A collaborative study with the Parkinson's Institute, Sunnyvale, CA (USA)
Objective/Rationale:
The heart, particularly the conduction system, is influenced by the parasympathetic and sympathetic nervous systems. Recently, early-occurring Parkinson’s disease-related Lewy... -
Program-non-specific Funding, 2008Evaluation of Pioglitazone CSF Penetration
Promising Outcomes of Original Grant:
In our original grant we assessed whether the antidiabetic compound pioglitazone can be neuroprotective in a non-human primate model of Parkinson’s disease. We...
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Our funding programs support basic, translational and clinical research from academia and industry.