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The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2023Development of a Protein Biomarker Panel to Measure Parkinson’s Disease Heterogeneity and Progression
Study Rationale: According to The Michael J. Fox Foundation, the need for biomarkers that provide an objective assessment for Parkinson’s disease (PD) “has become more urgent as more projects enter...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Interrogating LRRK2 Variants Common in Asian Populations to Discover Unique Biomarkers for Parkinson’s Disease
Study Rationale: Mutations in the LRRK2 gene are the most common genetic cause of Parkinson's disease (PD). Many studies have focused on the LRRK2 G2019S mutation found in Caucasians, and less is...
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Parkinson’s Disease Therapeutics Pipeline Program, 2023Development of Parkin Activators for the Treatment of Parkinson’s Disease
Study Rationale: Impaired function of cell structures called mitochondria plays a key role in the pathology of Parkinson’s disease (PD): alpha-synuclein accumulation damages mitochondria, dopamine...
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Research Grant, 2023Subtyping Parkinson’s Disease Using Genetic and Intestinal Inflammation Biomarkers
Study Rationale: Although Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide, no drugs are currently available to treat or prevent the condition because the...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Targeting a Phospholipid Unique to Mitochondrial Membranes as a Therapeutic for Parkinson’s Disease
Study Rationale: Mitochondria are energy-generating structures vital to the health of all cells. In Parkinson’s disease (PD), mitochondrial dysfunction leads to neuronal degeneration and to the motor...
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Circuits & Cellular Targets for PD’s Symptoms, 2023Unbiased Identification of New Targets for Deep Brain Stimulation to Treat Gait and Balance Impairments in Parkinson’s Disease
Study Rationale: Over time, people with Parkinson’s disease (PD) develop problems with their ability to walk that can cause serious injuries and curtail their independence. Mice with a particular...
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Our funding programs support basic, translational and clinical research from academia and industry.