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The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Therapeutic Pipeline Program, 2021Understand Me for Life: An Intelligibility App for Parkinson's Disease
Study Rationale:
Approximately 90% of people with Parkinson’s develop speech and language problems over the course of the disease, and more than half of these speakers experience problems with... -
Research Grant, 2021Hypoxia (Lowering Oxygen Levels) as a Novel Treatment for Parkinson’s Disease
Study Rationale:
Many anecdotes suggest that people with Parkinson’s disease (PD) can experience a marked improvement in symptoms when they travel to the mountains or during flights at high altitude... -
Target Advancement Program, 2021Modulation of Epigenetic Regulator HDAC4 as a Parkinson’s Treatment
Study Rationale:
Scientists can take skin cells from people with Parkinson’s disease (PD), turn them into stem cells, and then engineer them into dopamine neurons, the cell type lost in PD. Our... -
Therapeutic Pipeline Program, 2021Dietary Interventions to Slow and Improve Parkinson’s Symptoms by Restructuring the Gut Microbiome and Decreasing Inflammation
Study Rationale:
There is a link between the gut and the brain in Parkinson’s disease (PD), and gut bacteria may play an important role. Gut bacteria they affect the bowel mucus barrier, produce... -
Priority Biology, 2021LRRK2 Regulation of Melanoma Progression
Study Rationale:
People with Parkinson's disease (PD) are more likely to develop melanoma, and people with melanoma are more likely to develop PD than the general population. Additionally, melanoma... -
Therapeutic Pipeline Program, 2021RNA Targeting Small Molecules as Therapeutics for Parkinson's
Study Rationale:
Abnormal clumping of the protein alpha-synuclein is a hallmark of Parkinson's disease (PD) and a likely cause of neurodegeneration and, ultimately, symptoms. One of the causes...
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Our funding programs support basic, translational and clinical research from academia and industry.