The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Biomarkers to Support Therapeutic Trials Program, 2025Ultra-sensitive Quantification of Phosphorylated LRRK2 in Biofluids from Clinical Trials of Therapeutic Candidates
Study Rationale: LRRK2 is a protein for which inappropriate activation is associated with Parkinson’s disease (PD). Investigators are therefore pursuing the activity of LRRK2 as a potential...
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Research Grant, 2025Developing an ELISA Immunoassay for Monitoring Phosphorylation of Proteins Associated with Parkinson’s Disease
Study Rationale: As Parkinson’s disease (PD) progresses, one of the molecular changes that occurs is an increase in the number of phosphate groups that are added to proteins. In this project, we will...
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Research Grant, 2025Assessment of Artificial Intelligence (AI) and Blood-Brain Barrier Technology
Study Rationale: Companies are currently using artificial intelligence (AI) to design and develop new drugs and developing new ways to get drugs across the protective blood-brain barrier (BBB) and...
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Accelerating Biological Understanding and Therapeutic Translation for PD-Biology, 2025Studying SCAMPs: Membrane Proteins that Control Trafficking of Alpha-synuclein
Study Rationale: Parkinson’s disease (PD) progresses with the death of nerve cells in the brain. Some forms of the disease run in families due to mutations in important genes. One of these genes...
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Neuronal Synuclein Disease Endotypes 2024, 2025Testing Biofluid Samples from the Arizona Study of Aging and Neurodegenerative Disorders for Alpha-synuclein and Biomarkers of Alzheimer’s Disease
Study Rationale: The Arizona Study of Aging and Neurodegenerative Disorders (AZSAND) has amassed a comprehensive collection of samples and longitudinal clinicopathological data. In this project, we...
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Freezing of Gait Program, 2025AID-FOG: Artificial Intelligence-driven Freezing of Gait Detection in the Home
Study Rationale: Freezing of gait (FOG) is a symptom that causes many people with Parkinson’s disease (PD) to suddenly lose their ability to take a step while walking, creating a high risk for falling...
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Our funding programs support basic, translational and clinical research from academia and industry.