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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Freezing of Gait Program, 2025
    Treating Freezing of Gait in Parkinson’s Disease Using an ADHD Drug that Reduces Neural Cross-talk: A Multi-center Multi-modal Approach

    Study Rationale: Freezing of gait affects four out of five people with Parkinson’s disease (PD), yet this debilitating symptom is not fully treated by any PD medication available. Research has shown...

  • Parkinson’s Disease Therapeutics Pipeline Program, 2024
    Investigation of a Novel Therapeutic Approach for Non-motor Symptoms of Parkinson’s Disease

    Study Rationale:                  

    Parkinson's disease (PD) is characterized by both motor symptoms and non-motor symptoms. While progress has been made in addressing motor symptoms, non-motor...

  • Research Grant, 2025
    The BioFINDER Studies: Identifying Disease Stages and Effects of Co-morbidities in Neuronal Synuclein Disease

    Study Rationale: Neuronal synuclein disease (NSD) is the underlying cause of Parkinson’s disease (PD) and similar disorders. Recently, new tests have allowed us to measure signs of NSD before symptoms...

  • Spring 2022 RFA: Therapeutic Pipeline Program Pre-Clinical, 2024
    Exploring Paxalisib as a Novel Therapeutic for Parkinson’s Disease

    Study Rationale: Studies in preclinical models of Parkinson’s disease (PD) and in postmortem PD brains suggest that a signaling pathway that is switched on by activation of a protein called...

  • ASAP CRN Competitive Renewal Opportunity, 2024
    Investigating How Alpha-synuclein-rich Neurons in Olfactory Circuits Respond to Environmental Triggers at the Initiation of Parkinson Disease
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    Study Rationale: To slow the progression of Parkinson disease (PD), we need to understand how, where and why the illness starts. It is estimated that most individuals with PD experience a significant...

  • Neuronal Synuclein Disease Endotypes 2024, 2025
    Using the Biopark Cohort to Study Neuronal Synuclein Disease Types

    Study Rationale: To study the pathogenic processes underlying Parkinson’s disease (PD), we have recruited a cohort of several hundred people, including those with hereditary PD, those that carry PD...

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