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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2013
    Neuromelanin in Circulating Phagocytes May Reveal Early Neurodegeneration in Parkinson’s Disease

    Objective/Rationale:             
    A normal function of inflammation is to recruit phagocytic white blood cells (think PACMAN) to clear away the damaged cells. We postulate that debris laden PACMEN re...

  • Therapeutic Pipeline Program, 2013
    Pre-clinical Evaluation of Neuroprotective Small Molecule Erythropoietin Receptor Agonists in the Treatment of Parkinson’s Disease

    Objective/Rationale:             
    Erythropoietin (EPO) receptor is present throughout the body and plays a role in both red blood cell production and tissue protection.  STATegics has discovered small...

  • Synuclein Therapeutic Acceleration Program, 2013
    Quinpramine for Parkinson’s Disease

    Objective/Rationale:             
    A part of Parkinson’s disease progression involves abnormal aggregation of normal brain proteins into knots of insoluble irritant material. The protein involved in...

  • Therapeutic Pipeline Program, 2013
    Development of Trehalose as a Disease-modifying Treatment for Parkinson’s Disease

    Objective/Rationale:             
    The development of Parkinson’s disease (PD) is linked to the accumulation of the toxic protein alpha-synuclein. Systems within neurons able to clear alpha-synuclein...

  • Biosample and Tissue Resource, 2013
    From Genetic Risk Toward Genetic Prognosis

    Objective/Rationale: 
    The progression and prognosis of Parkinson’s disease (PD) varies considerably between individual patients — ranging from a manageable, functional decline to an aggressive course...

  • Research Grant, 2013
    Development of Highly Sensitive Immunoassays for pS129 Alpha-synuclein in Human Samples

    Objective/Rationale:             
    The development of disease-modifying therapies in Parkinson’s disease requires the availability of quantitative biomarkers for use in primary diagnosis, monitoring...

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