The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Community Fast Track, 2004Finding genetic risk factors for Parkinson’s disease in genetically isolated populations
What causes Parkinson's disease is largely unknown but both environmental factors and genetic risk factors play a role. Over the years researchers have identified mutations in genes that are...
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Community Fast Track, 2004Mechanisms of HIPK2-dependent Survival & Differentiation of Midbrain Dopaminergic Neurons - a Chemical Genetic Target for Parkinson's Disease
Regulation of gene expression is critical for neuronal development, survival, differentiation, and axon/dendritic arborization. While several transcription factors have been shown to be important for...
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Community Fast Track, 2004Vaccine-induced Neuroprotection in an Animal Model of Parkinson's Disease
There is a growing appreciation that immune responses can significantly improve neuronal survival after injury or in neurodegenerative diseases. Immune-deficient mice have reduced neurorepair...
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Community Fast Track, 2004Identification of Factors that Promote Midbrain Dopaminergic Fate from Embryonic Stem Cells and Neural Stem Cells
Parkinson's disease is a progressive neurological disorder caused by the degeneration of midbrain dopaminergic neurons. While cell transplantation has shown promising clinical benefit in some patients...
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Community Fast Track, 2004Characterization of DJ-1 Null Transgenic Mice
The protein DJ-1 has been implicated to play a role in neurodegenerative diseases, such as multiple system atrophy and Parkinson's disease (PD). Mutations in the DJ-1 gene have been linked to an...
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Community Fast Track, 2004The role of nociceptin/orphanin FQ in regulation of motor behavior and induction of parkinsonism
Nociceptin/orphanin FQ (N/OFQ) is an opioid-like neuropeptide discovered in the mid 90's, which activates a G-protein coupled receptor, the NOP receptor. N/OFQ and its receptor are diffusely expressed...
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Our funding programs support basic, translational and clinical research from academia and industry.