The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2024Validation of Functional Staging of Parkinson’s Disease Using the Critical Path for Parkinson’s (CPP) Integrated Parkinson’s Database
Study Rationale: Researchers recently proposed defining Parkinson’s disease (PD) based on a test for abnormal alpha-synuclein in spinal fluid and adopting a staging system based on measures (or scales...
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Postural Instability and Gait Disturbances, 2009The Role of White Matter Pathology in the Development of the Postural Instability and Gait Disturbance (PIGD) Type of Parkinson's Disease (PD)-1
Objective/Rationale:
It is not clear why a subset of patients with Parkinson's disease develop postural instability and gait disturbances (PIGD), while others do not. White matter (WM) changes that... -
Therapeutic Pipeline Program, 2015Inhibitors of Alpha-synuclein Oligomers for the Treatment of Parkinson’s Disease
Study Rationale:
The alpha-synuclein protein forms oligomers (protein clumps) that cause toxicity in the brains of individuals with Parkinson’s disease (PD). We have developed methods that can measure... -
Therapeutics Development Initiative, 2006Evaluation of the Neuroprotective Peptide NAPVSIPQ in Models of Parkinson's Disease
Parkinson's disease is characterized by the selective loss of dopamine neurons, which leads to reduced control of voluntary locomotor activities. The cause of this degeneration is unknown; however...
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Research Grant, 2014Validation of the Movement Disorders Society’s Clinical Criteria of Parkinson’s Disease
Study Rationale:
Diagnosis of Parkinson’s disease (PD) and other causes of parkinsonism is not always an easy task for physicians. An accurate diagnosis, however, is an essential aspect of care for... -
Rapid Response Innovation Awards, 2010Increasing Endogenous Neurogenesis Using Neurosteroids: A Novel Therapeutic Strategy to Treat Parkinson's Disease
Objective/Rationale:
We will test a locally produced brain chemical that increases the generation of new neurons to replace the damaged neurons in Parkinson disease (PD). The production of this...
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Our funding programs support basic, translational and clinical research from academia and industry.