The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2013Deep Sequencing Mass Spectrometry to Identify Biomarkers of Parkinson’s Disease in Cerebrospinal Fluid
Objective/Rationale:
Parkinson’s disease typically goes undetected until clinical diagnosis based on physical manifestations such as rigidity, resting tremor and slowness of movement. Unfortunately... -
Parkin Biology, 2013Deciphering and Exploiting the Neuroprotective Activity of Parkin
Objective/Rationale:
Mutations in the Parkin gene are responsible for parkinsonism, and there is evidence that Parkin is inactivated in sporadic (cause unknown) Parkinson's disease... -
Research Grant, 2013Effect of NPT088 in Alpha-synuclein Overexpressing Models
Promising Outcomes of Original Grant:
NeuroPhage technology simultaneously targets multiple misfolded proteins (e.g., alpha-synuclein, amyloid-beta, phosphorylated tau) involved in neurodegenerative... -
Clinical Intervention Awards, 2013Dipraglurant for Levodopa-Induced Dyskinesia Pre-phase IIB Studies
Study Rationale:
Dipraglurant is a modulator of the metabotropic glutamate receptor 5 (mGluR5). Blockade of this receptor has been shown to have anti-parkinsonian and anti-dyskinetic... -
Neurotrophic Factors Challenge, 2013Exploring a Novel Neurotrophic Factor to Protect the Nigrostriatal Dopaminergic System and Alleviate Motor Deficits
Objective/Rationale:
Safety and effectiveness in brain delivery remain two major challenges in developing novel neuroprotective agents to treat Parkinson’s disease (PD) patients. This... -
Cognition Biomarkers, 2013Insulin-like Growth Factor-1 and DAT Imaging as Biomarkers of Early Cognitive Impairment in Parkinson’s Disease
Objective/Rationale:
Evidence supports that the protein insulin-like growth factor-1 (IGF-1) may be involved in cognitive deficits. An earlier study found that low serum IGF-1 levels...
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Our funding programs support basic, translational and clinical research from academia and industry.