The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Rapid Response Innovation Awards, 2010Biomarkers and Immunotherapy for Parkinson's Disease
Objective/Rationale:
We theorize that the interplay between the immune system and the brain plays a substantive role in the progression of Parkinson’s disease. Moreover, we posit that the immune system... -
Critical Challenges in PD: Alpha-synuclein Neuroimaging, 2010Development and Screening of Contrast Agents for In-vivo Imaging of Parkinson's Disease
Promising Outcomes of Original Grant:
The goals of the original grant were to screen a library of compounds to identify leads for non-invasive imaging of PD pathology. We used cell culture models of... -
Rapid Response Innovation Awards, 2010Mechanism and Modulation of Alpha-Synuclein Expression
Promising Outcomes of Original Grant:
In the initial grant, we tested the hypothesis that GATA-2 is a direct regulator of alpha-synuclein expression in dopaminergic neurons and therefore represents a... -
Rapid Response Innovation Awards, 2010Increased Dopamine Transporter Function as an Early Phenotype of PD, Prior to Dopamine Neuron Cell Death
Objective/Rationale:
Since the identification of a number of Parkinson’s disease genes in humans, much effort has been spent at developing pre-clinical models of the disease. However, most genetic pre... -
Novel Hypotheses in Parkinson's Disease, 2010Gait disturbances in Parkinson's disease: new links to alpha-synuclein pathology
Objective/Rationale:
Gait disturbances in PD are characteristic of advanced Parkinson’s disease (PD); they are extremely disabling to the patient and can frequently lead to patient falls, fractures... -
Novel Hypotheses in Parkinson's Disease, 2010Identifying and Localizing Toxic Oligomeric A-Syn with Morphology Specific Nanobodies
Objective/Rationale:
Aggregation and deposition of the protein, a-synuclein (a-syn), has been strongly correlated with PD and other related neurodegenerative disorders. The a-syn protein occurs in a...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.