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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Therapeutic Pipeline Program, 2013
    Pre-clinical Evaluation of Neuroprotective Small Molecule Erythropoietin Receptor Agonists in the Treatment of Parkinson’s Disease

    Objective/Rationale:             
    Erythropoietin (EPO) receptor is present throughout the body and plays a role in both red blood cell production and tissue protection.  STATegics has discovered small...

  • Aligning Science Across Parkinson's, 2021
    Understanding and Manipulating Cellular and Circuit-level Vulnerability to Neurodegeneration in Parkinson’s Disease
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    Study Rationale:
    Many people with Parkinson’s disease develop untreatable cognitive symptoms, including problems with attention, decision-making, and dementia at late stages of the disease, due to...

  • Edmond J. Safra Movement Disorders Research Career Development Award, 2024
    Towards a Better Understanding of Treatment-refractory Gait Issues in Parkinson’s Disease

    Study Rationale: Freezing of gait (FOG) is a sudden arrest of gait despite the intention to continue walking, often while a person is turning, walking in a confined space or is in a situation that...

  • Rapid Response Innovation Awards, 2009
    Plasma Biomarker Screen for Neurodegeneration and Signaling Proteins

    Objective/Rationale:
    The cells and tissues of the body can “communicate” with one another using small secreted proteins that can be found in the blood. There are several hundred of these cellular...

  • Novel Approaches to Drug Discovery for Parkinson's Disease, 2007
    Fisetin and Derivatives as Neuroprotective Drugs for the Treatment of Parkinson's Disease

    Objective/Rationale: 

    Glutathione (GSH) is an antioxidant produced naturally by cells thereby providing them with a defense against oxidative stress. There is good evidence that GSH levels decrease in...

  • MJFF Research Grant, 2010
    Clinical Assessment of Patients with PD Who Underwent DAT Scan and FDG PET at the Early Stages of Their Extra-Pyramidal Disorder as Part of Their Initial Workup

    Objective/Rationale: 
    Ashkenazi Jewish PD patients in Israel have a 14% chance of carrying the G2019S LRRK2 mutation and 18% of carrying mutations in the GBA gene. Little is known on the association...

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