The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2009Characterizing Transgenic Pre-Clinical Models that Express a Mutant LRRK2 Gene Selectively in Adulthood
Objective/Rationale:
Mutations of the gene LRRK2 are identified in both familial and sporadic Parkinson’s disease (PD). How mutation of the LRRK2 gene causes neuronal dysfunction in PD remains to be... -
Postural Instability and Gait Disturbances, 2009Role of the Posterior Parietal Cortex and Pedunculopontine Nucleus in the Pathophysiology of Freezing of Gait: An MRI and TMS Study
Objective/Rationale:
Although disturbances in the posterior parietal cortex (PPC) and pedunculopontine nucleus (PPN) are thought to be involved in the development of freezing of gait (FOG) in PD... -
Postural Instability and Gait Disturbances, 2009Neuroanatomical Correlates of Dopamine Responsive and Non-responsive Gait and Balance Impairment in Parkinson's Disease
Objective/Rationale:
Parkinson’s is more than a motor disorder that responds to dopamine replacement. Dopamine non-responsive features account for much of the disability that develops with disease... -
Postural Instability and Gait Disturbances, 2009Relationship between REM Behavior Disorder and Freezing of Gait in Parkinson's Disease
Objective/Rationale:
Many people with REM sleep behavior disorder (RBD), a disease associated with disturbance of sleep, eventually develop Parkinson’s disease. Dysfunction and degeneration of... -
Postural Instability and Gait Disturbances, 2009Determining the Neural Correlates of Freezing of Gait in Parkinson's Disease Using Functional Magnetic Resonance Imaging
Objective/Rationale:
Freezing of Gait (FOG) in Parkinson’s disease occurs when a person’s feet become suddenly ‘frozen’ while walking or turning. FOG is a leading cause of falls, and responds poorly to... -
Postural Instability and Gait Disturbances, 2009The Role of White Matter Pathology in the Development of the Postural Instability and Gait Disturbance (PIGD) Type of Parkinson's Disease (PD)-1
Objective/Rationale:
It is not clear why a subset of patients with Parkinson's disease develop postural instability and gait disturbances (PIGD), while others do not. White matter (WM) changes that...
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Our funding programs support basic, translational and clinical research from academia and industry.