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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023
    Using a Virally Encoded, Single-chain Antibody as a Noninvasive Gene Therapy for Parkinson’s Disease

    Study Rationale: The main pathological hallmarks of Parkinson’s disease (PD) are the degeneration of dopamine-producing brain cells and the accumulation of protein aggregates containing misfolded...

  • Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023
    (Supplement) Cellular Brain Repair for Parkinson’s Disease: Preclinical Therapeutic Validation of Biomaterial-supported Cell Transplants Coupled with Immunosuppression

    Study Rationale: Although transplantation of stem cell-derived brain cells is a promising therapeutic approach for Parkinson’s disease (PD), only a small fraction of the cells that are transplanted...

  • Data-Driven Subtyping and Stratification Program, 2023
    Identifying Distinct Patterns in Parkinson’s Disease Progression Using Integrative, Data-driven Subtype Analysis

    Study Rationale: Parkinson’s disease (PD) is associated with diverse motor and non-motor manifestation that progress gradually over time. Although this progression differs from individual to...

  • Research Grant, 2023
    (Supplement) PET Imaging Probe Development for Alpha-synuclein

    Study Rationale: Alpha-synuclein is a protein that can clump to form Lewy bodies and lewy neurites, which are a hallmark of Parkinson's disease. Being able to identify these clumps in living patients...

  • Research Grant, 2023
    Leveraging Gene Expression Data to Redefine Parkinson’s Disease and the Pathways Driving Disease in Different Individuals

    Study Rationale: People with Parkinson’s disease (PD) share some common problems, such as stiffness, slowness of movement and tremors. However, these symptoms vary in severity, and individuals often...

  • Parkinson’s Pathway Molecular Data Analysis Program, 2023
    Characterization of Parkinson’s Disease Clinical Subtypes Using Multiple Immunologic and Genetic Markers

    Study Rationale: Parkinson’s disease (PD) is an umbrella term that encompasses a highly heterogeneous domain of clinical manifestations, which makes the development of effective therapeutic strategies...

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