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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Cognition Biomarkers, 2014
    miRNA Markers of Cognition

    In previous MJFF-funded research, these researchers identified four promising microRNAs (which regulate gene expression) associated with cognitive status. They profiled the miRNAs...

  • Cognition Biomarkers, 2013
    Alpha-synuclein and Cognitive Decline in Parkinson’s Disease

    Variability in the SNCA gene (which encodes alpha-synuclein, the protein that clumps in Parkinson’s disease) is a major risk factor for PD. Using next-generation...

  • Cognition Biomarkers, 2013
    Assessment of Plasma Glucosylceramides and Ceramides as Biomarkers of Cognitive Impairment in Parkinson's Disease

    Metabolism of the lipids glucosylceramide and ceramide is altered in Parkinson’s disease (PD). GBA mutations in this pathway, causing a build-up of glucosylceramide, increase the...

  • Cognition Biomarkers, 2013
    Insulin-like Growth Factor-1 and DAT Imaging as Biomarkers of Early Cognitive Impairment in Parkinson’s Disease

    Evidence supports that the protein insulin-like growth factor-1 (IGF-1) may be involved in cognitive deficits. An earlier study found that low serum IGF-1 levels...

  • Cognition Biomarkers, 2013
    [18F]flubatine: a novel biomarker of cognition in Parkinson's disease

    Mild cognitive impairment and dementia are frequent symptoms of moderate to advanced Parkinson’s disease (PD). Brain positron emission tomography (PET) study findings confirm post...

  • Cognition Biomarkers, 2013
    Validation of Novel and Traditional Quantitative EEG Biomarkers

    Cognitive problems commonly add to the disability of the motor symptoms of Parkinson’s disease (PD), but there are no highly effective treatments for cognitive dysfunction in PD....

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