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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Therapeutic Pipeline Program, 2021
    Using Ketamine to Treat Depression in Parkinson’s Disease

    Study Rationale:
    Depression affects around half of people with Parkinson’s disease (PD). However, existing antidepressants are not effective in treating these symptoms in PD and new treatments are...

  • Therapeutic Pipeline Program, 2015
    Improving Access to Depression Care in Parkinson’s Disease: A Telehealth Approach

    Study Rationale:                   
    There is a critical need for treatments that address depression and barriers to care among the approximately 5 million people living with Parkinson’s disease (PD)...

  • Resource: Utilizing Samples from the Arizona Parkinson’s Di, 2012
    Preferential Loss of Serotonin Axon Subtypes in Depression in Parkinson's Disease

    Objective/Rationale:
    Depression occurs in Parkinson’s disease (PD) much more frequently than in the general population, and is a major factor contributing to decreased quality of life for affected...

  • Research Grant, 2020
    Identification of Therapeutic Circuits to Address Anxiety and Depression Symptoms in Parkinson’s Disease

    Study Rationale: Parkinson’s disease patients often experience depression and anxiety. Addressing these non-motor symptoms has not been the focus of Parkinson’s disease research though psychiatric...

  • PD Subtypes, 2007
    Prediction of Death, Dementia, Disability, Depression from the Time Course of UPDRS Motor Status

    Parkinson’s disease is progressive. Early on, its effects are relatively minor, affecting mainly movement and causing shaking of the limbs. Later on, serious events -- early death, dementia...

  • Fast Track, 2001
    PET Neuroimaging Study of the Brain Serotonin Transporter in Parkinson's Disease: Relationship to Clinical Depression

    Approximately 40% of patients with Parkinson's disease (PD) suffer from depression, which in many cases is more disabling than the impairment of motor function. Since the original discovery by Oleh...

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