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Funded Studies

Optimizing Vibration Therapy to Improve Gait and Balance in Parkinson's Disease

Study Rationale:
Many people who have Parkinson's disease experience freezing of gait, which is an inability to walk despite intention to walk. Unfortunately, drugs rarely help with this problem. Early evidence has shown that vibration therapy applied to the feet can help reduce freezing of gait.

Hypothesis:
We predict that vibration therapy applied to the feet will help reduce the occurrence and severity of freezing of gait.

Study Design:
We will first determine the best therapeutic dose of vibration (frequency and amplitude) and duration (length of time) of vibration therapy. We will then perform a randomized controlled trial to test the efficacy of vibration therapy compared to a placebo.

Impact on Diagnosis/Treatment of Parkinson's Disease:
If effective, vibration therapy could be used to treat freezing of gait in people with Parkinson's. Because the vibration device is non-invasive, lightweight, portable, contains a rechargeable battery and is worn on the feet (inside of a shoe), it is ideal for use in everyday life.

Next Steps for Development:
If successful, this study will support larger Phase II clinical studies, which will further assess the safety and effectiveness of this device.


Researchers

  • Ingrid Pretzer-Aboff, RN, PhD

    Richmond, VA United States


  • Leslie Jameleh Cloud, MD

    Richmond, VA United States


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