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Funded Studies

Edward A. Fon, MD, FRCP(C)

Professor and Scientific Director at Montreal Neurological Institute, McGill University

Location: Montreal QC Canada

Edward Fon is a neurologist-scientist at the Montreal Neurological Institute (MNI) specializing in movement disorders and Professor in the Department of Neurology and Neurosurgery at McGill University. He is Director of the FRQS Quebec Parkinson Network (http://rpq-qpn.ca/en/) and Scientific Director of the MNI. His laboratory has made contributions in understanding the function and cell biology of Parkinson's disease (PD) genes and in understanding how defects in these genes lead to PD. He has focused on how Parkin and PINK1, two proteins encoded by recessive PD genes, regulate mitochondrial quality control. He has also made contributions towards understanding the function of other PD genes, including GBA, α-synuclein, LRRK2, TMEM175 and DJ-1. He has established the infrastructure at the MNI to study these PD gene in patient-derived induced pluripotent stem cells, differentiated into neurons, glia and 3D brain organoids (https://www.mcgill.ca/neuro/open-science/open-science-platforms/eddu). He also helped establish the MNI C-BIGr Open biorepository (https://www.mcgill.ca/c-bigneuro/) and the Tanenbaum Open Science Institute (https://www.mcgill.ca/neuro/open-science).


Associated Grants

  • Illuminating the Dark Genome of Parkinson’s Disease

    2021


  • Effects of LRRK2 Variants on GCase Activity in iPSC-derived Dopamine Neurons and Microglia

    2020


  • Small-Molecule Inhibitor of Alpha-Synuclein Propagation in the Treatment of Parkinson's Disease

    2017


  • Investigating the Effect of Parkin on Alpha-synuclein Propagation

    2016


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