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Funded Studies

Edward A. Fon, MD, FRCP(C)

Professor and Scientific Director at Montreal Neurological Institute, McGill University

Location: Montreal QC Canada

Edward Fon is a neurologist-scientist at the Montreal Neurological Institute (MNI) specializing in movement disorders and Professor in the Department of Neurology and Neurosurgery at McGill University. He is Director of the FRQS Quebec Parkinson Network ( and Scientific Director of the MNI. His laboratory has made contributions in understanding the function and cell biology of Parkinson's disease (PD) genes and in understanding how defects in these genes lead to PD. He has focused on how Parkin and PINK1, two proteins encoded by recessive PD genes, regulate mitochondrial quality control. He has also made contributions towards understanding the function of other PD genes, including GBA, α-synuclein, LRRK2, TMEM175 and DJ-1. He has established the infrastructure at the MNI to study these PD gene in patient-derived induced pluripotent stem cells, differentiated into neurons, glia and 3D brain organoids ( He also helped establish the MNI C-BIGr Open biorepository ( and the Tanenbaum Open Science Institute (

Associated Grants

  • Gaining Mechanistic Insights into PINK1 Genetic Variants


  • Simultaneous Profiling of Gene Expression Patterns from Pooled Cell Samples of Large Parkinson’s Disease Cohorts


  • Illuminating the Dark Genome of Parkinson’s Disease


  • Effects of LRRK2 Variants on GCase Activity in iPSC-derived Dopamine Neurons and Microglia


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