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Ian G. Ganley, PhD

Professor of Cellular Homeostasis at University of Dundee
Location: Dundee United Kingdom

Ian Ganley, PhD, is a professor in the MRC Protein Phosphorylation and Ubiquitylation Unit at The University of Dundee. He received his bachelors and Master of Biochemistry from the University of Oxford, UK and obtained his doctoral degree from the University of Cambridge, United Kingdom. Following postdoctoral work at Stanford University and Memorial Sloan Kettering Cancer Center, Ian established his own group at the University of Dundee to understand the molecular regulation of mitophagy – a process that is dysregulated in Parkinson’s disease. His group has elucidated how key kinase complexes, such as ULK1 and AMPK, control mitophagy initiation and progression. They also developed the groundbreaking mito-QC reporter to visualize mitophagy, a tool now widely used across academia and industry. In recognition of his leadership in cell biology, he received the prestigious 2025 Hooke Medal and was elected Fellow of the Royal Society of Edinburgh.


Associated Grants

  • Role of TFEB Pathway Activators and ISR Inhibitors on Alpha-synuclein Associated Impaired Mitophagy in the a Pre-clinical Model Brain

    2025


  • Assessing the Effects of USP30 Inhibitors on the Removal of Damaged Mitochondria in Nerve Cells

    2022


  • Determining the Ligase and DUB Landscape of Mitochondrial and Alpha-synuclein Turnover

    2020


  • Studying the Parkin Protein in New Pre-Clinical Models

    2017


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