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Funded Studies

Jean-Christophe Rochet, PhD

Professor, Department of Medicinal Chemistry and Molecular Pharmacology at Purdue University

John and Donna Krenicki Director, Purdue Institute for Integrative Neuroscience

Location: West Lafayette, IN United States

Jean-Christophe (Chris) Rochet obtained his PhD degree in the Department of Biochemistry at the University of Alberta (Edmonton, Canada) in 1998. From 1999-2002, Dr. Rochet worked as a post-doctoral fellow with Dr. Peter Lansbury in the Department of Neurology at Harvard Medical School. His postdoctoral research (supported by a fellowship from the Human Frontier Science Program Organization) focused on the role of alpha-synuclein self-assembly in Parkinson's disease.

In the fall of 2002, Dr. Rochet joined the Department of Medicinal Chemistry and Molecular Pharmacology at Purdue University, where he is now a professor. The overall goals of his research program are to understand mechanisms of neurotoxicity and neuroprotection in PD by characterizing PD-related gene products (e.g., alpha-synuclein, DJ-1), and to use this information to develop new therapeutic strategies.

Dr. Rochet's honors include a Melvin Yahr Fellowship from the International Federation of Parkinson's Disease and a PhRMA Foundation Sabbatical Fellowship in Pharmacology and Toxicology.

Associated Grants

  • Effects of Chemical Modifications on Aggregation of Alpha-synuclein


  • Developing a Method for Detecting Alpha-synuclein in the Acidic Cell Compartments in Which It Accumulates


  • Effects of Post-translational Modifications on Alpha-synuclein Aggregation


  • Neuroprotective Effects of NFE2L1 in Parkinson's Models


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