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Michael James Higley, MD, PhD

Associate Professor, Neuroscience at Yale University

Location: New Haven, CT United States

Michael Higley, MD, PhD, is an Associate Professor in the Department of Neuroscience at the Yale School of Medicine. He received his MD/PhD from the University of Pennsylvania and postdoctoral training at Harvard Medical School. 

Dr. Higley has 25 years of experience using electrophysiology and optical imaging to study the organization and function of the mammalian nervous system. He has made fundamental contributions to our understanding of how GABAergic inhibition and neuromodulation influence neural activity and behavior via regulation of synaptic transmission and excitability. He has established and applied advanced methodologies for fluorescence imaging to study neural circuits, both ex vivo and in the neocortex of awake, behaving mice. In recent years, the Higley laboratory has pioneered the combined application of these methods to bridge the gaps between molecular, cellular, and systems neuroscience.

Associated Grants

  • Understanding and Manipulating Cellular and Circuit-level Vulnerability to Neurodegeneration in Parkinson’s Disease


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