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  • A pathway for Parkinson’s Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain
    2018
    RESTRICTED
    Title: A pathway for Parkinson’s Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain
    Author(s): Herschel S Dhekne, Yasukatsu Izumi, Rachel C Gomez, Francesca Tonelli, Federico Diez, Birgitt Schüle, Martin Steger, Dario R. Alessi, Suzanne R Pfeffer
    Journal Name: eLife
    Publisher: eLife Sciences Publications, Ltd
    Vol: 7
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.7554/elife.40202
    Best OA location URL: https://doi.org/10.7554/elife.40202
    Citation Count: 170
  • Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates
    2018
    RESTRICTED
    Title: Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates
    Author(s): Songye Li, Zhengxin Cai, Xiaoai Wu, Daniel Holden, Richard Pracitto, Michael Kapinos, Hong Gao, David Labaree, Nabeel Nabulsi, Richard E. Carson, Yiyun Huang
    Journal Name: ACS Chemical Neuroscience
    Publisher: American Chemical Society (ACS)
    Vol: 10
    Issue #: 3
    Start Page: 1544
    End Page: 1554
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1021/acschemneuro.8b00526
    Best OA location URL: https://europepmc.org/articles/pmc6810685?pdf=render
    Citation Count: 69
  • Targeting the pedunculopontine nucleus in Parkinson's disease: Time to go back to the drawing board
    2018
    RESTRICTED
    Title: Targeting the pedunculopontine nucleus in Parkinson's disease: Time to go back to the drawing board
    Author(s): Roger L. Albin, D. James Surmeier, Cecilia Tubert, Martin Sarter, Martijn Müller, Nicolaas I. Bohnen, William T. Dauer
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 33
    Issue #: 12
    Start Page: 1871
    End Page: 1875
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27540
    Best OA location URL: http://deepblue.lib.umich.edu/bitstream/2027.42/147041/2/mds27540_am.pdf
    Citation Count: 16
  • RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway
    2018
    RESTRICTED
    Title: RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway
    Author(s): Jin‐Mi Heo, Alban Ordureau, Sharan Swarup, João A. Paulo, Kuang Shen, David M. Sabatini, J. Wade Harper
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 4
    Issue #: 11
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc, cc-by-nc
    DOI - Digital Object Identifier: 10.1126/sciadv.aav0443
    Best OA location URL: https://advances.sciencemag.org/content/advances/4/11/eaav0443.full.pdf
    Citation Count: 125
  • Serum Insulin-Like Growth Factor-1 in Parkinson's Disease; Study of Cerebrospinal Fluid Biomarkers and White Matter Microstructure
    2018
    RESTRICTED
    Title: Serum Insulin-Like Growth Factor-1 in Parkinson's Disease; Study of Cerebrospinal Fluid Biomarkers and White Matter Microstructure
    Author(s): Farzaneh Ghazi Sherbaf, Bahram Mohajer, Amir Ashraf‐Ganjouei, Mahtab Mojtahed Zadeh, Ali Javinani, Hossein Sanjari Moghaddam, Mehdi Shirin Shandiz, Mohammad Hadi Aarabi
    Journal Name: Frontiers in Endocrinology
    Publisher: Frontiers Media SA
    Vol: 9
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fendo.2018.00608
    Best OA location URL: https://www.frontiersin.org/articles/10.3389/fendo.2018.00608/pdf
    Citation Count: 15
  • A detailed clinical study of pain in 1957 participants with early/moderate Parkinson's disease
    2018
    RESTRICTED
    Title: A detailed clinical study of pain in 1957 participants with early/moderate Parkinson's disease
    Author(s): Monty Silverdale, Christopher Kobylecki, Lewis Kass-Iliyya, Pablo Martı́nez-Martı́n, Michael Lawton, Sarah Cotterill, K. Ray Chaudhuri, Huw R. Morris, Fahd Baig, Nigel Williams, Leon Hubbard, Michèle Hu, Donald G. Grosset
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 56
    Issue #:
    Start Page: 27
    End Page: 32
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2018.06.001
    Best OA location URL: http://www.prd-journal.com/article/S1353802018302608/pdf
    Citation Count: 77
  • Dissociation between urate and blood pressure in mice and in people with early Parkinson's disease
    2018
    RESTRICTED
    Title: Dissociation between urate and blood pressure in mice and in people with early Parkinson's disease
    Author(s): Xiqun Chen, Chizoba C. Umeh, Robert E. Tainsh, Danielle Feng, M. Helen Maguire, Fuxing Zuo, Maryam Rahimian, Robert A. Logan, Xinliumei Wang, Alberto Ascherio, Eric A. Macklin, Emmanuel Buys, Michael A. Schwarzschild
    Journal Name: EBioMedicine
    Publisher: Elsevier BV
    Vol: 37
    Issue #:
    Start Page: 259
    End Page: 268
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.ebiom.2018.10.039
    Best OA location URL: http://www.thelancet.com/article/S2352396418304572/pdf
    Citation Count: 8
  • Early detection of Parkinson’s disease through patient questionnaire and predictive modelling
    2018
    RESTRICTED
    Title: Early detection of Parkinson’s disease through patient questionnaire and predictive modelling
    Author(s): R. Prashanth, Sumantra Dutta Roy
    Journal Name: International Journal of Medical Informatics
    Publisher: Elsevier BV
    Vol: 119
    Issue #:
    Start Page: 75
    End Page: 87
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.ijmedinf.2018.09.008
    Best OA location URL: https://arxiv.org/pdf/1810.01855
    Citation Count: 54
  • Essential tremor plus is more common than essential tremor: Insights from the reclassification of a cohort of patients with lower limb tremor
    2018
    RESTRICTED
    Title: Essential tremor plus is more common than essential tremor: Insights from the reclassification of a cohort of patients with lower limb tremor
    Author(s): Rajasumi Rajalingam, David P. Breen, Anthony E. Lang, Alfonso Fasano
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 56
    Issue #:
    Start Page: 109
    End Page: 110
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2018.06.029
    Best OA location URL:
    Citation Count: 52
  • Increased expression of toll-like receptor 3, an anti-viral signaling molecule, and related genes in Alzheimer's disease brains
    2018
    RESTRICTED
    Title: Increased expression of toll-like receptor 3, an anti-viral signaling molecule, and related genes in Alzheimer's disease brains
    Author(s): Douglas G. Walker, Tiffany M. Tang, Lih‐Fen Lue
    Journal Name: Experimental Neurology
    Publisher: Elsevier BV
    Vol: 309
    Issue #:
    Start Page: 91
    End Page: 106
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.expneurol.2018.07.016
    Best OA location URL: https://europepmc.org/articles/pmc6151184?pdf=render
    Citation Count: 32
  • Phenotypic Reprogramming of Striatal Neurons into Dopaminergic Neuron-like Cells in the Adult Mouse Brain
    2018
    RESTRICTED
    Title: Phenotypic Reprogramming of Striatal Neurons into Dopaminergic Neuron-like Cells in the Adult Mouse Brain
    Author(s): Wenze Niu, Tong Zang, Lei Lei Wang, Yuhua Zou, Chunli Zhang
    Journal Name: Stem Cell Reports
    Publisher: Elsevier BV
    Vol: 11
    Issue #: 5
    Start Page: 1156
    End Page: 1170
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.stemcr.2018.09.004
    Best OA location URL: http://www.cell.com/article/S2213671118303898/pdf
    Citation Count: 37
  • Phosphorylation of Parkin at serine 65 is essential for its activationin vivo
    2018
    RESTRICTED
    Title: Phosphorylation of Parkin at serine 65 is essential for its activationin vivo
    Author(s): Thomas G. McWilliams, Erica Barini, Risto Pohjolan-Pirhonen, Simon Philip Brooks, François Singh, Sophie Burel, Kristin Balk, Atul Kumar, Lambert Montava-Garriga, Alan R. Prescott, Sidi Mohamed Hassoun, François Mouton-Liger, Graeme Ball, Rachel Hills, Axel Knebel, Ayşe Ulusoy, Donato A. Di Monte, J. Tamjar, Odetta Antico, Kyle Fears, Laura A. Smith, Riccardo Brambilla, Eino Palin, Miko Valori, Johanna Eerola‐Rautio, Pentti J. Tienari, Olga Corti, Stephen B. Dunnett, Ian G. Ganley, Anu Suomalainen, Miratul M. K. Muqit
    Journal Name: Open Biology
    Publisher: The Royal Society
    Vol: 8
    Issue #: 11
    Start Page: 180108
    End Page: 180108
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1098/rsob.180108
    Best OA location URL: https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.180108
    Citation Count: 83
  • Predicting early cognitive decline in newly-diagnosed Parkinson's patients: A practical model
    2018
    RESTRICTED
    Title: Predicting early cognitive decline in newly-diagnosed Parkinson's patients: A practical model
    Author(s): Olivia Hogue, Hubert H. Fernández, Darlene Floden
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 56
    Issue #:
    Start Page: 70
    End Page: 75
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2018.06.031
    Best OA location URL: https://europepmc.org/articles/pmc6425482?pdf=render
    Citation Count: 19
  • Subthalamic nucleus deep brain stimulation reduces freezing of gait subtypes and patterns in Parkinson's disease
    2018
    RESTRICTED
    Title: Subthalamic nucleus deep brain stimulation reduces freezing of gait subtypes and patterns in Parkinson's disease
    Author(s): Michael T. Barbe, Claudia Barthel, Lung Chi Chen, Nic Van Dyck, Thomas Brücke, F. Seijo, Esther Suaréz San Martín, Claire Haegelen, Marc Vérin, Martin Amarell, Steve Gill, Alan Whone, Mauro Porta, Domenico Servello, Gereon R. Fink, François Alesch, Bastiaan R. Bloem, Lars Timmermann
    Journal Name: Brain Stimulation
    Publisher: Elsevier BV
    Vol: 11
    Issue #: 6
    Start Page: 1404
    End Page: 1406
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.brs.2018.08.016
    Best OA location URL: https://doi.org/10.1016/j.brs.2018.08.016
    Citation Count: 5
  • The E3 Ubiquitin Ligases TRIM17 and TRIM41 Modulate α-Synuclein Expression by Regulating ZSCAN21
    2018
    RESTRICTED
    Title: The E3 Ubiquitin Ligases TRIM17 and TRIM41 Modulate α-Synuclein Expression by Regulating ZSCAN21
    Author(s): Irina Lassot, Stéphan Mora, Suzanne Lesage, Barbara A. Zieba, Emmanuelle Coque, Christel Condroyer, Jozef P. Bossowski, Barbara Mojsa, Cécilia Marelli, Caroline Soulet, Christelle Tesson, Iria Carballo‐Carbajal, Ariadna Laguna, Graziella Mangone, Miquel Vila, Alexis Brice, Solange Desagher
    Journal Name: Cell Reports
    Publisher: Elsevier BV
    Vol: 25
    Issue #: 9
    Start Page: 2484
    End Page: 2496.e9
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.celrep.2018.11.002
    Best OA location URL: http://www.cell.com/article/S2211124718317315/pdf
    Citation Count: 31
  • The G2019S mutation in LRRK2 imparts resiliency to kinase inhibition
    2018
    RESTRICTED
    Title: The G2019S mutation in LRRK2 imparts resiliency to kinase inhibition
    Author(s): Kaela Kelly, Shijie Wang, Ravindra Boddu, Yong Li, Omar Moukha-Chafiq, Corinne E. Augelli‐Szafran, Andrew B. West
    Journal Name: Experimental Neurology
    Publisher: Elsevier BV
    Vol: 309
    Issue #:
    Start Page: 1
    End Page: 13
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.expneurol.2018.07.012
    Best OA location URL: https://doi.org/10.1016/j.expneurol.2018.07.012
    Citation Count: 41
  • The small molecule alpha-synuclein misfolding inhibitor, NPT200-11, produces multiple benefits in an animal model of Parkinson’s disease
    2018
    RESTRICTED
    Title: The small molecule alpha-synuclein misfolding inhibitor, NPT200-11, produces multiple benefits in an animal model of Parkinson’s disease
    Author(s): D. L. Price, Maya A. Koike, Adnan Khan, Wolfgang Wrasidlo, Edward Rockenstein, Eliezer Masliah, Douglas W. Bonhaus
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 8
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-018-34490-9
    Best OA location URL: https://www.nature.com/articles/s41598-018-34490-9.pdf
    Citation Count: 106
  • Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
    2018
    RESTRICTED
    Title: Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
    Author(s): Richard D. Gordon, Eduardo A Albornoz, Daniel C. Christie, Monica Langley, Vinod Kumar, Susanna Mantovani, Avril A. B. Robertson, Mark S. Butler, Dominic B. Rowe, Luke A.J. O’Neill, Anumantha G. Kanthasamy, Kate Schroder, Matthew A. Cooper, Trent M. Woodruff
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 10
    Issue #: 465
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aah4066
    Best OA location URL: https://stm.sciencemag.org/content/scitransmed/10/465/eaah4066.full.pdf
    Citation Count: 485
  • Metabolomic Profiling of Bile Acids in an Experimental Model of Prodromal Parkinson’s Disease
    2018
    RESTRICTED
    Title: Metabolomic Profiling of Bile Acids in an Experimental Model of Prodromal Parkinson’s Disease
    Author(s): Stewart F. Graham, Nolwen L. Rey, Zafer Ugur, Ali Yılmaz, Eric Sherman, Michael Maddens, Ray O. Bahado‐Singh, Katelyn Becker, Emily Schulz, Lindsay Meyerdirk, Jennifer A. Steiner, Jiyan Ma, Patrik Brundin
    Journal Name: Metabolites
    Publisher: MDPI AG
    Vol: 8
    Issue #: 4
    Start Page: 71
    End Page: 71
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.3390/metabo8040071
    Best OA location URL: https://www.mdpi.com/2218-1989/8/4/71/pdf
    Citation Count: 35
  • The Parkinson's progression markers initiative (PPMI) – establishing a PD biomarker cohort
    2018
    RESTRICTED
    Title: The Parkinson's progression markers initiative (PPMI) – establishing a PD biomarker cohort
    Author(s): Kenneth Marek, Sohini Chowdhury, Andrew Siderowf, Shirley Lasch, Christopher S. Coffey, Chelsea Caspell‐Garcia, Tanya Simuni, Danna Jennings, Caroline M. Tanner, John Q. Trojanowski, Leslie M. Shaw, John Seibyl, Norbert Schuff, Andrew Singleton, Karl Kieburtz, Arthur W. Toga, Brit Mollenhauer, Doug Galasko, Lana M. Chahine, Daniel Weintraub, Tatiana Foroud, Duygu Tosun, Kathleen L. Poston, Vanessa Arnedo, Mark Frasier, Todd Sherer, Parkinson’s Progression Markers Initiative
    Journal Name: Annals of Clinical and Translational Neurology
    Publisher: Wiley
    Vol: 5
    Issue #: 12
    Start Page: 1460
    End Page: 1477
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/acn3.644
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.644
    Citation Count: 320
  • The vermiform appendix impacts the risk of developing Parkinson’s disease
    2018
    RESTRICTED
    Title: The vermiform appendix impacts the risk of developing Parkinson’s disease
    Author(s): Bryan A. Killinger, Zachary Madaj, Jacek Sikora, Nolwen L. Rey, Alec J. Haas, Yamini Vepa, Daniel Lindqvist, Honglei Chen, Paul M. Thomas, Patrik Brundin, Lena Brundin, Viviane Labrie
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 10
    Issue #: 465
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aar5280
    Best OA location URL: https://stm.sciencemag.org/content/scitransmed/10/465/eaar5280.full.pdf
    Citation Count: 202
  • δ-Secretase-cleaved Tau stimulates Aβ production via upregulating STAT1-BACE1 signaling in Alzheimer’s disease
    2018
    RESTRICTED
    Title: δ-Secretase-cleaved Tau stimulates Aβ production via upregulating STAT1-BACE1 signaling in Alzheimer’s disease
    Author(s): Zhentao Zhang, Xiaoguang Li, Zhi-Hao Wang, Mingke Song, Shan Ping Yu, Seong Su Kang, Xia Liu, Zhaohui Zhang, Manling Xie, Gong‐Ping Liu, Jian‐Zhi Wang, Keqiang Ye
    Journal Name: Molecular Psychiatry
    Publisher: Springer Science and Business Media LLC
    Vol: 26
    Issue #: 2
    Start Page: 586
    End Page: 603
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/s41380-018-0286-z
    Best OA location URL: https://europepmc.org/articles/pmc6684859?pdf=render
    Citation Count: 54
  • Parkin targets NOD2 to regulate astrocyte endoplasmic reticulum stress and inflammation
    2018
    RESTRICTED
    Title: Parkin targets NOD2 to regulate astrocyte endoplasmic reticulum stress and inflammation
    Author(s): Komudi Singh, Han Kim, Sharada Tilve, Kaiyuan Wu, Herbert M. Geller, Michael N. Sack
    Journal Name: Glia
    Publisher: Wiley
    Vol: 66
    Issue #: 11
    Start Page: 2427
    End Page: 2437
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/glia.23482
    Best OA location URL: https://europepmc.org/articles/pmc6275110?pdf=render
    Citation Count: 40
  • β2‐adrenoreceptor medications and risk of Parkinson disease
    2018
    RESTRICTED
    Title: β2‐adrenoreceptor medications and risk of Parkinson disease
    Author(s): Susan Searles Nielsen, Anat Gross, Alejandra Camacho‐Soto, Allison W. Willis, Brad A. Racette
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Vol: 84
    Issue #: 5
    Start Page: 683
    End Page: 693
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/ana.25341
    Best OA location URL: https://europepmc.org/articles/pmc6881195?pdf=render
    Citation Count: 58
  • The Luxembourg Parkinson’s Study: A Comprehensive Approach for Stratification and Early Diagnosis
    2018
    RESTRICTED
    Title: The Luxembourg Parkinson’s Study: A Comprehensive Approach for Stratification and Early Diagnosis
    Author(s): Géraldine Hipp, Michel Vaillant, Nico J. Diederich, Kirsten Roomp, Venkata Satagopam, Peter Banda, Estelle Sandt, Kathleen Mommaerts, Sabine Schmitz, Laura Longhino, Alexandra Schweicher, Anne-Marie Hanff, Béatrice Nicolai, Pierre Kolber, Dorothea Reiter, Lukas Pavelka, Sylvia Binck, Claire Pauly, Lars Geffers, Fay Betsou, Manon Gantenbein, Jochen Klucken, Thomas Gasser, Michele T.M. Hu, Rudi Balling, Rejko Krüger
    Journal Name: Frontiers in Aging Neuroscience
    Publisher: Frontiers Media SA
    Vol: 10
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnagi.2018.00326
    Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnagi.2018.00326/pdf
    Citation Count: 54
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