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  • Independent and joint effects of the MAPT and SNCA genes in Parkinson disease
    2011
    RESTRICTED
    Title: Independent and joint effects of the MAPT and SNCA genes in Parkinson disease
    Author(s): Alexis Elbaz, Owen A. Ross, John P. A. Ioannidis, Alexandra I. Soto‐Ortolaza, Frédéric Moisan, Jan Aasly, Grazia Annesi, Maria Bozi, Laura Brighina, Marie-Christine Chartier-Harlin, Alain Destée, Carlo Ferrarese, Alessandro Ferraris, J. M. Gibson, Suzana Gispert, Georgios M. Hadjigeorgiou, Barbara Jasińska‐Myga, Christine Klein, Rejko Krüger, Jean‐Charles Lambert, Katja Lohmann, Simone van de Loo, Marie‐Anne Loriot, Timothy Lynch, George D. Mellick, Eugénie Mutez, Christer Nilsson, Grzegorz Opala, Andreas Puschmann, Aldo Quattrone, Manu Sharma, Peter A. Silburn, Leonidas Stefanis, Ryan J. Uitti, Enza Maria Valente, Carles Vilariño‐Güell, Karin Wirdefeldt, Zbigniew K. Wszołek, Georgia Xiromerisiou, Demetrius M. Maraganore, Matthew J. Farrer
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Vol: 69
    Issue #: 5
    Start Page: 778
    End Page: 792
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/ana.22321
    Best OA location URL: https://europepmc.org/articles/pmc3082599?pdf=render
    Citation Count: 86
  • Use of ibuprofen and risk of Parkinson disease
    2011
    RESTRICTED
    Title: Use of ibuprofen and risk of Parkinson disease
    Author(s): Xiang Gao, Honglei Chen, Michael A. Schwarzschild, Alberto Ascherio
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 76
    Issue #: 10
    Start Page: 863
    End Page: 869
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0b013e31820f2d79
    Best OA location URL: https://europepmc.org/articles/pmc3059148?pdf=render
    Citation Count: 276
  • Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2
    2011
    RESTRICTED
    Title: Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2
    Author(s): Xianming Deng, Nicolas Dzamko, Alan R. Prescott, Paul Davies, Qingsong Liu, Qingkai Yang, Jiing-Dwan Lee, Matthew P. Patricelli, Tyzoon Nomanbhoy, Dario R. Alessi, Nathanael S. Gray
    Journal Name: Nature Chemical Biology
    Publisher: Springer Science and Business Media LLC
    Vol: 7
    Issue #: 4
    Start Page: 203
    End Page: 205
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/nchembio.538
    Best OA location URL: https://europepmc.org/articles/pmc3287420?pdf=render
    Citation Count: 379
  • A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions
    2011
    RESTRICTED
    Title: A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions
    Author(s): Sheila M. Fleming, Caitlin Mulligan, Franziska Richter, Farzad Mortazavi, Vincent Lemesre, Carmen Frías, Chunni Zhu, Angela Stewart, Illana Gozes, Bruce H. Morimoto, Marie‐Françoise Chesselet
    Journal Name: Molecular and Cellular Neuroscience
    Publisher: Elsevier BV
    Vol: 46
    Issue #: 3
    Start Page: 597
    End Page: 606
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.mcn.2010.12.011
    Best OA location URL: https://europepmc.org/articles/pmc3046337?pdf=render
    Citation Count: 66
  • Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice
    2011
    RESTRICTED
    Title: Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice
    Author(s): Beate Winner, HL Melrose, Chen Zhao, KM Hinkle, Mei Yue, Caroline Kent, Adam Braithwaite, Sina Ogholikhan, Robert Aigner, Jürgen Winkler, Matthew J. Farrer, F. H. Gage
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 41
    Issue #: 3
    Start Page: 706
    End Page: 716
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2010.12.008
    Best OA location URL: https://europepmc.org/articles/pmc3059106?pdf=render
    Citation Count: 170
  • Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression
    2011
    RESTRICTED
    Title: Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression
    Author(s): Min Shi, Joshua M. Bradner, Aneeka M. Hancock, Kathryn A. Chung, Joseph F. Quinn, Elaine R. Peskind, Douglas Galasko, Joseph Jankovic, Cyrus P. Zabetian, Hojoong M. Kim, James B. Leverenz, Thomas J. Montine, Carmen Ginghină, Un Jung Kang, Kevin C. Cain, Yu Wang, Jan Aasly, David S. Goldstein, Jing Zhang
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Vol: 69
    Issue #: 3
    Start Page: 570
    End Page: 580
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/ana.22311
    Best OA location URL: https://europepmc.org/articles/pmc3117674?pdf=render
    Citation Count: 376
  • Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration
    2011
    RESTRICTED
    Title: Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration
    Author(s): Maryna Baydyuk, Madeline Nguyen, Baoji Xu
    Journal Name: Experimental Neurology
    Publisher: Elsevier BV
    Vol: 228
    Issue #: 1
    Start Page: 118
    End Page: 125
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.expneurol.2010.12.018
    Best OA location URL: https://europepmc.org/articles/pmc3041148?pdf=render
    Citation Count: 64
  • Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patients
    2011
    RESTRICTED
    Title: Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patients
    Author(s): Hua She, Qian Yang, Kennie R. Shepherd, Yoland Smith, Gary W. Miller, Claudia Testa, Zixu Mao
    Journal Name: Journal of Clinical Investigation
    Publisher: American Society for Clinical Investigation
    Vol: 121
    Issue #: 3
    Start Page: 930
    End Page: 940
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1172/jci43871
    Best OA location URL: http://www.jci.org/articles/view/43871/files/pdf
    Citation Count: 141
  • Mitochondrial DNA haplogroups and mutations in children with acquired central demyelination
    2011
    RESTRICTED
    Title: Mitochondrial DNA haplogroups and mutations in children with acquired central demyelination
    Author(s): Sunita Venkateswaran, Kangni Zheng, Maria Luisa Sacchetti, Donald Gagné, Douglas L. Arnold, A. Dessa Sadovnick, Stephen W. Scherer, Brenda Banwell, Amit Bar‐Or, David K. Simon
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 76
    Issue #: 9
    Start Page: 774
    End Page: 780
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0b013e31820ee1bb
    Best OA location URL: https://europepmc.org/articles/pmc3053335?pdf=render
    Citation Count: 15
  • Mutational analysis of parkin and PINK1 in multiple system atrophy
    2011
    RESTRICTED
    Title: Mutational analysis of parkin and PINK1 in multiple system atrophy
    Author(s): Janet Brooks, Henry Houlden, Anna Melchers, Ansha J. Islam, Jinhui Ding, Abi Li, Reema Paudel, Tamás Révész, Janice L. Holton, Nicholas W. Wood, Andrew J. Lees, Andrew Singleton, Sonja W. Scholz
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 32
    Issue #: 3
    Start Page: 548.e5
    End Page: 548.e7
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2009.11.020
    Best OA location URL: https://europepmc.org/articles/pmc3934211?pdf=render
    Citation Count: 16
  • Personality Characteristics and Motor Skills Attributed to Occupations in Parkinson Disease
    2011
    RESTRICTED
    Title: Personality Characteristics and Motor Skills Attributed to Occupations in Parkinson Disease
    Author(s): Nicole M. Gatto, Yvette Bordelon, Margaret Gatz, Beate Ritz
    Journal Name: Cognitive and Behavioral Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 24
    Issue #: 1
    Start Page: 18
    End Page: 25
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1097/wnn.0b013e318218c5eb
    Best OA location URL: https://europepmc.org/articles/pmc3656654?pdf=render
    Citation Count: 16
  • White matter lesions in Parkinson disease
    2011
    RESTRICTED
    Title: White matter lesions in Parkinson disease
    Author(s): Nicolaas I. Bohnen, Roger L. Albin
    Journal Name: Nature Reviews Neurology
    Publisher: Springer Science and Business Media LLC
    Vol: 7
    Issue #: 4
    Start Page: 229
    End Page: 236
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/nrneurol.2011.21
    Best OA location URL: https://europepmc.org/articles/pmc3739056?pdf=render
    Citation Count: 176
  • Solution-Phase Parallel Synthesis and SAR of Homopiperazinyl Analogs as Positive Allosteric Modulators of mGlu4
    2011
    RESTRICTED
    Title: Solution-Phase Parallel Synthesis and SAR of Homopiperazinyl Analogs as Positive Allosteric Modulators of mGlu4
    Author(s): Yiu‐Yin Cheung, Rocio Zamorano, Annie L. Blobaum, C. David Weaver, P. Jeffrey Conn, Craig W. Lindsley, Colleen M. Niswender, Corey R. Hopkins
    Journal Name: ACS Combinatorial Science
    Publisher: American Chemical Society (ACS)
    Vol: 13
    Issue #: 2
    Start Page: 159
    End Page: 165
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1021/co1000508
    Best OA location URL: https://europepmc.org/articles/pmc3057427?pdf=render
    Citation Count: 6
  • In vivo demonstration that α-synuclein oligomers are toxic
    2011
    RESTRICTED
    Title: In vivo demonstration that α-synuclein oligomers are toxic
    Author(s): Beate Winner, Roberto Jappelli, Samir K. Maji, Paula Desplats, Leah Boyer, Stefan Aigner, Claudia Hetzer, Thomas Löher, Marçal Vilar, Silvia Campioni, Christos Tzitzilonis, Alice Soragni, Sebastian Jessberger, Helena Mira, Antonella Consiglio, Emiley Pham, Eliezer Masliah, Fred H. Gage, Roland Riek
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 108
    Issue #: 10
    Start Page: 4194
    End Page: 4199
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.1100976108
    Best OA location URL: https://europepmc.org/articles/pmc3053976?pdf=render
    Citation Count: 1267
  • MAPT H1 haplotype is a risk factor for essential tremor and multiple system atrophy
    2011
    RESTRICTED
    Title: MAPT H1 haplotype is a risk factor for essential tremor and multiple system atrophy
    Author(s): Carles Vilariño‐Güell, Alexandra I. Soto‐Ortolaza, Alex Rajput, Deborah C. Mash, Spyridon Papapetropoulos, Rajesh Pahwa, Kelly E. Lyons, Ryan J. Uitti, Zbigniew K. Wszołek, Dennis W. Dickson, Matthew J. Farrer, Owen A. Ross
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 76
    Issue #: 7
    Start Page: 670
    End Page: 672
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0b013e31820c30c1
    Best OA location URL: https://europepmc.org/articles/pmc3053340?pdf=render
    Citation Count: 68
  • Substantia nigra hyperechogenicity with LRRK2 G2019S mutations
    2011
    RESTRICTED
    Title: Substantia nigra hyperechogenicity with LRRK2 G2019S mutations
    Author(s): Norbert Brüggemann, Johann Hagenah, Kaili Stanley, Christine Klein, Cuiling Wang, Deborah Raymond, Laurie J. Ozelius, Susan Bressman, Rachel Saunders‐Pullman
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 26
    Issue #: 5
    Start Page: 885
    End Page: 888
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23644
    Best OA location URL: https://europepmc.org/articles/pmc3082617?pdf=render
    Citation Count: 31
  • Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms
    2011
    RESTRICTED
    Title: Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms
    Author(s): Maike Hartlage‐Rübsamen, Markus Morawski, Alexander Waniek, Carsten Jäger, Ulrike Zeitschel, Birgit Koch, Holger Cynis, Stephan Schilling, Reinhard Schliebs, Hans‐Ulrich Demuth, Steffen Rößner
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Vol: 121
    Issue #: 6
    Start Page: 705
    End Page: 719
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1007/s00401-011-0806-2
    Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00401-011-0806-2.pdf
    Citation Count: 49
  • Evaluation of the D3 dopamine receptor selective agonist/partial agonist PG01042 on l-dopa dependent animal involuntary movements in rats
    2011
    RESTRICTED
    Title: Evaluation of the D3 dopamine receptor selective agonist/partial agonist PG01042 on l-dopa dependent animal involuntary movements in rats
    Author(s): Lindsay R. Riddle, Rakesh Kumar, Suzy A. Griffin, Peter Grundt, Amy Hauck Newman, Robert R. Luedtke
    Journal Name: Neuropharmacology
    Publisher: Elsevier BV
    Vol: 60
    Issue #: 2-3
    Start Page: 284
    End Page: 294
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.neuropharm.2010.09.011
    Best OA location URL: https://europepmc.org/articles/pmc3820002?pdf=render
    Citation Count: 20
  • TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers
    2011
    RESTRICTED
    Title: TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers
    Author(s): NiCole A. Finch, Minerva M. Carrasquillo, Matthew Baker, Nicola J. Rutherford, Giovanni Coppola, Mariely DeJesus-Hernandez, Richard Crook, Talisha A. Hunter, Roberta Ghidoni, Luisa Benussi, Julia E. Crook, Elizabeth Finger, K. J. Hantanpaa, Anna Karydas, Pheth Sengdy, John Gonzalez, William W. Seeley, Nancy Johnson, Thomas G. Beach, Marek-Marsel Mesulam, Gianluigi Forloni, Andrew Kertesz, David S. Knopman, Ryan J. Uitti, Charles L. White, Richard J. Caselli, Carol F. Lippa, Eileen H. Bigio, Zbigniew K. Wszołek, Giuliano Binetti, Ian R. Mackenzie, Bruce L. Miller, Bradley F. Boeve, Steven G. Younkin, Dennis W. Dickson, Ronald C. Petersen, Neill R. Graff‐Radford, Daniel H. Geschwind, Rosa Rademakers
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 76
    Issue #: 5
    Start Page: 467
    End Page: 474
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0b013e31820a0e3b
    Best OA location URL: https://europepmc.org/articles/pmc3034409?pdf=render
    Citation Count: 211
  • α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
    2011
    RESTRICTED
    Title: α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
    Author(s): Christian Hansen, Élodie Angot, Ann-Louise Bergström, Jennifer A. Steiner, Laura Pieri, Gesine Paul, Tiago F. Outeiro, Ronald Melki, Pekka Kallunki, Karina Fog, Jia Yi Li, Patrik Brundin
    Journal Name: Journal of Clinical Investigation
    Publisher: American Society for Clinical Investigation
    Vol: 121
    Issue #: 2
    Start Page: 715
    End Page: 725
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1172/jci43366
    Best OA location URL: http://www.jci.org/articles/view/43366/files/pdf
    Citation Count: 736
  • Coffee, ADORA2A, and CYP1A2: the caffeine connection in Parkinson’s disease
    2011
    RESTRICTED
    Title: Coffee, ADORA2A, and CYP1A2: the caffeine connection in Parkinson’s disease
    Author(s): Rita Popat, Stephen K. Van Den Eeden, Caroline M. Tanner, Freya Kamel, David M. Umbach, Karen Marder, Richard Mayeux, Beate Ritz, G. Webster Ross, Helen Petrovitch, Barbara Topol, V. McGuire, Sadie Costello, Angelika D. Manthripragada, Audrey Southwick, R Myers, Lorene M. Nelson
    Journal Name: European Journal of Neurology
    Publisher: Wiley
    Vol: 18
    Issue #: 5
    Start Page: 756
    End Page: 765
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1111/j.1468-1331.2011.03353.x
    Best OA location URL: https://europepmc.org/articles/pmc3556904?pdf=render
    Citation Count: 93
  • Essential tremor and Parkinson's disease: Lack of a link
    2011
    RESTRICTED
    Title: Essential tremor and Parkinson's disease: Lack of a link
    Author(s): Charles H. Adler, Holly A. Shill, Thomas G. Beach
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 26
    Issue #: 3
    Start Page: 372
    End Page: 377
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23509
    Best OA location URL: https://europepmc.org/articles/pmc3070808?pdf=render
    Citation Count: 56
  • From reinforcement learning models to psychiatric and neurological disorders
    2011
    RESTRICTED
    Title: From reinforcement learning models to psychiatric and neurological disorders
    Author(s): Tiago V. Maia, Michael J. Frank
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 14
    Issue #: 2
    Start Page: 154
    End Page: 162
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/nn.2723
    Best OA location URL: https://europepmc.org/articles/pmc4408000?pdf=render
    Citation Count: 619
  • Olfaction in Parkin heterozygotes and compound heterozygotes
    2011
    RESTRICTED
    Title: Olfaction in Parkin heterozygotes and compound heterozygotes
    Author(s): Roy N. Alcalay, Andrew Siderowf, Ruth Ottman, Elise Caccappolo, Helen Mejia‐Santana, Ming Tang, Llency Rosado, Elan D. Louis, Diana Ruiz, Cheryl Waters, Stanley Fahn, Lucien J. Côté, Steven J. Frucht, Blair Ford, Martha Orbe-Reilly, Barbara Ross, Miguel Verbitsky, Sergey Kisselev, Cynthia Comella, Amy Colcher, Danna Jennings, Martha Nance, Susan Bressman, William K. Scott, Caroline M. Tanner, Susan F. Mickel, Michael Rezak, Kevin Novak, Joseph H. Friedman, Ronald F. Pfeiffer, Laura Marsh, Bradley C. Hiner, Lorraine N. Clark, Karen Marder
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 76
    Issue #: 4
    Start Page: 319
    End Page: 326
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0b013e31820882aa
    Best OA location URL: https://europepmc.org/articles/pmc3034420?pdf=render
    Citation Count: 47
  • Cyclin-G-associated kinase modifies -synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study
    2011
    RESTRICTED
    Title: Cyclin-G-associated kinase modifies -synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study
    Author(s): Alexandra Dumitriu, Chris D. Pacheco, Jemma B. Wilk, Katherine E. Strathearn, Jeanne C. Latourelle, Stefano Goldwurm, Gianni Pezzoli, Jean‐Christophe Rochet, Susan Lindquist, Richard H. Myers
    Journal Name: Human Molecular Genetics
    Publisher: Oxford University Press (OUP)
    Vol: 20
    Issue #: 8
    Start Page: 1478
    End Page: 1487
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1093/hmg/ddr026
    Best OA location URL: https://europepmc.org/articles/pmc3063983?pdf=render
    Citation Count: 60
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