MJFF Publications

SRCP: a comprehensive pipeline for accurate annotation and quantification of circRNAs

2021

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Title: SRCP: a comprehensive pipeline for accurate annotation and quantification of circRNAs

Author(s): Alon Rabin, Michela Zaffagni, Reut Ashwal-Fluss, Inés Lucía Patop, Aarti Jajoo, Shlomo Shenzis, Liran Carmel, Sebastián Kadener

Journal Name: Genome Biology

Publisher: Springer Science and Business Media LLC

Vol: 22

Issue #: 1

Start Page:

End Page:

Publication Date: 2021-09-23

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1186/s13059-021-02497-7

Best OA location URL: https://genomebiology.biomedcentral.com/track/pdf/10.1186/s13059-021-02497-7

Citation Count: 11

A zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons

2021

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Title: A zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons

Author(s): Ghahyun J. Kim, Han Mo, Harrison Liu, Zhihao Wu, Steven Chen, Jiashun Zheng, Xiang Zhao, Daryl Nucum, James Shortland, Longping Peng, Mannuel Elepano, Benjamin C. Tang, Steven H. Olson, Nick A. Paras, Hao Li, Adam R. Renslo, Michelle R. Arkin, Bo Huang, Bingwei Lu, Marina Sirota, Su Guo

Journal Name: eLife

Publisher: eLife Sciences Publications, Ltd

Vol: 10

Issue #:

Start Page:

End Page:

Publication Date: 2021-09-22

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.7554/elife.69795

Best OA location URL: https://doi.org/10.7554/elife.69795

Citation Count: 21

Additive effects of mGluR2 positive allosteric modulation, mGluR2 orthosteric stimulation and 5-HT2AR antagonism on dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset

2021

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Title: Additive effects of mGluR2 positive allosteric modulation, mGluR2 orthosteric stimulation and 5-HT2AR antagonism on dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset

Author(s): Stephen G. Nuara, Jim C. Gourdon, Shawn P. Maddaford, Philippe Huot

Journal Name: Naunyn-Schmiedeberg's Archives of Pharmacology

Publisher: Springer Science and Business Media LLC

Vol: 394

Issue #: 12

Start Page: 2381

End Page: 2388

Publication Date: 2021-09-22

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1007/s00210-021-02162-7

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Citation Count: 1

Glucocerebrosidase Activity is not Associated with Parkinson's Disease Risk or Severity

2021

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Title: Glucocerebrosidase Activity is not Associated with Parkinson's Disease Risk or Severity

Author(s): Nurit Omer, Nir Giladi, Tanya Gurevich, Anat Bar‐Shira, Mali Gana‐Weisz, Tal Glinka, Orly Goldstein, Meir Kestenbaum, Jesse M. Cedarbaum, Omar S. Mabrouk, Kyle Fraser, Julia Shirvan, Avi Orr‐Urtreger, Anat Mirelman, Avner Thaler

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 37

Issue #: 1

Start Page: 190

End Page: 195

Publication Date: 2021-09-22

Open Access(OA) Status: RESTRICTED

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1002/mds.28792

Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292990

Citation Count: 19

Growth Factor Therapy for Parkinson’s Disease: Alternative Delivery Systems

2021

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Title: Growth Factor Therapy for Parkinson’s Disease: Alternative Delivery Systems

Author(s): Sarah Jarrin, Abrar Hakami, Ben Newland, Eilís Dowd

Journal Name: Journal of Parkinson's Disease

Publisher: IOS Press

Vol: 11

Issue #: s2

Start Page: S229

End Page: S236

Publication Date: 2021-09-22

Open Access(OA) Status: RESTRICTED

License: cc-by-nc

DOI - Digital Object Identifier: 10.3233/jpd-212662

Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd212662?id=journal-of-parkinsons-disease%2Fjpd212662

Citation Count: 6

Pharmacogenetic Predictors of Cannabidiol Response and Tolerability in Treatment‐Resistant Epilepsy

2021

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Title: Pharmacogenetic Predictors of Cannabidiol Response and Tolerability in Treatment‐Resistant Epilepsy

Author(s): Brittney Davis, T. Mark Beasley, Michelle D. Amaral, Jerzy P. Szaflarski, Tyler E. Gaston, Leslie P. Grayson, David Standaert, E. Martina Bebin, Nita A. Limdi

Journal Name: Clinical Pharmacology & Therapeutics

Publisher: Wiley

Vol: 110

Issue #: 5

Start Page: 1368

End Page: 1380

Publication Date: 2021-09-22

Open Access(OA) Status: RESTRICTED

License: cc-by-nc

DOI - Digital Object Identifier: 10.1002/cpt.2408

Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cpt.2408

Citation Count: 23

Fine mapping of the HLA locus in Parkinson’s disease in Europeans

2021

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Title: Fine mapping of the HLA locus in Parkinson’s disease in Europeans

Author(s): Eric Yu, Aditya Ambati, Maren Stolp Andersen, Lynne Krohn, Mehrdad Asghari Estiar, Prabhjyot Saini, Konstantin Senkevich, Yuri L. Sosero, Ashwin Ashok Kumar Sreelatha, Jennifer A. Ruskey, Farnaz Asayesh, Dan Spiegelman, Mathias Toft, Marte K. Viken, Manu Sharma, Cornelis Blauwendraat, Lasse Pihlstrøm, Emmanuel Mignot, Ziv Gan‐Or

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 7

Issue #: 1

Start Page:

End Page:

Publication Date: 2021-09-21

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-021-00231-5

Best OA location URL: https://www.nature.com/articles/s41531-021-00231-5.pdf

Citation Count: 36

Pathways to Parkinson’s disease: a spotlight on 14-3-3 proteins

2021

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Title: Pathways to Parkinson’s disease: a spotlight on 14-3-3 proteins

Author(s): Elena Giusto, Talene A. Yacoubian, Elisa Greggio, Laura Civiero

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 7

Issue #: 1

Start Page:

End Page:

Publication Date: 2021-09-21

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-021-00230-6

Best OA location URL: https://www.nature.com/articles/s41531-021-00230-6.pdf

Citation Count: 24

A Blueprint for the Conduct of Large, Multisite Trials in Telemedicine

2021

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Title: A Blueprint for the Conduct of Large, Multisite Trials in Telemedicine

Author(s): Patricia Commiskey, April W. Armstrong, Tumaini R. Coker, E. Ray Dorsey, John C. Fortney, Kenneth Gaines, Brittany Gibbons, Huong Q. Nguyen, Daisy R. Singla, Eva Szigethy, Elizabeth A. Krupinski

Journal Name: Journal of Medical Internet Research

Publisher: JMIR Publications Inc.

Vol: 23

Issue #: 9

Start Page: e29511

End Page: e29511

Publication Date: 2021-09-20

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.2196/29511

Best OA location URL: https://www.jmir.org/2021/9/e29511/PDF

Citation Count: 1

Coding and Noncoding Variation in LRRK2 and Parkinson's Disease Risk

2021

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Title: Coding and Noncoding Variation in LRRK2 and Parkinson's Disease Risk

Author(s): Julie Lake, Xylena Reed, Rebekah G. Langston, Mike A. Nalls, Ziv Gan‐Or, Mark Cookson, Andrew Singleton, Cornelis Blauwendraat, Hampton L. Leonard

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 37

Issue #: 1

Start Page: 95

End Page: 105

Publication Date: 2021-09-20

Open Access(OA) Status: RESTRICTED

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.1002/mds.28787

Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.28787

Citation Count: 17

Molecular Imaging of the Cholinergic System in Alzheimer and Lewy Body Dementias: Expanding Views

2021

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Title: Molecular Imaging of the Cholinergic System in Alzheimer and Lewy Body Dementias: Expanding Views

Author(s): Prabesh Kanel, Marc‐André Bedard, Meghmik Aghourian, Pedro Rosa‐Neto, Jean‐Paul Soucy, Roger L. Albin, Nicolaas I. Bohnen

Journal Name: Current Neurology and Neuroscience Reports

Publisher: Springer Science and Business Media LLC

Vol: 21

Issue #: 10

Start Page:

End Page:

Publication Date: 2021-09-20

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1007/s11910-021-01140-z

Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020458

Citation Count: 13

Age of Onset of Huntington's Disease in Carriers of Reduced Penetrance Alleles

2021

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Title: Age of Onset of Huntington's Disease in Carriers of Reduced Penetrance Alleles

Author(s): Erin McDonnell, Yuanjia Wang, Jill Goldman, Karen Marder

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 36

Issue #: 12

Start Page: 2958

End Page: 2961

Publication Date: 2021-09-18

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1002/mds.28789

Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688195

Citation Count: 4

Alpha-Synuclein and Lipids: The Elephant in the Room?

2021

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Title: Alpha-Synuclein and Lipids: The Elephant in the Room?

Author(s): Alessia Sarchione, Antoine Marchand, Jean‐Marc Taymans, Marie-Christine Chartier-Harlin

Journal Name: Cells

Publisher: MDPI AG

Vol: 10

Issue #: 9

Start Page: 2452

End Page: 2452

Publication Date: 2021-09-17

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.3390/cells10092452

Best OA location URL: https://www.mdpi.com/2073-4409/10/9/2452/pdf?version=1632375393

Citation Count: 21

Comprehensive subtyping of Parkinson’s disease patients with similarity fusion: a case study with BioFIND data

2021

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Title: Comprehensive subtyping of Parkinson’s disease patients with similarity fusion: a case study with BioFIND data

Author(s): Matthew Brendel, Chang Su, Yu Hou, Claire Henchcliffe, Fei Wang

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 7

Issue #: 1

Start Page:

End Page:

Publication Date: 2021-09-17

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-021-00228-0

Best OA location URL: https://www.nature.com/articles/s41531-021-00228-0.pdf

Citation Count: 13

echolocatoR: an automated end-to-end statistical and functional genomic fine-mapping pipeline

2021

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Title: echolocatoR: an automated end-to-end statistical and functional genomic fine-mapping pipeline

Author(s): Brian M. Schilder, Jack Humphrey, Towfique Raj

Journal Name: Bioinformatics

Publisher: Oxford University Press (OUP)

Vol: 38

Issue #: 2

Start Page: 536

End Page: 539

Publication Date: 2021-09-16

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1093/bioinformatics/btab658

Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060715

Citation Count: 22

Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition

2021

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Title: Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition

Author(s): Chelsie Kadgien, Anusha Kamesh, Austen J. Milnerwood

Journal Name: Molecular Brain

Publisher: Springer Science and Business Media LLC

Vol: 14

Issue #: 1

Start Page:

End Page:

Publication Date: 2021-09-16

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1186/s13041-021-00848-w

Best OA location URL: https://molecularbrain.biomedcentral.com/track/pdf/10.1186/s13041-021-00848-w

Citation Count: 8

Oromandibular Dystonia: A Clinical Examination of 2,020 Cases

2021

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Title: Oromandibular Dystonia: A Clinical Examination of 2,020 Cases

Author(s): Laura Scorr, Stewart A. Factor, Sahyli Perez Parra, Rachel Kaye, Randal C. Paniello, Scott A. Norris, Joel S. Perlmutter, Tobias Bäumer, Tatiana Usnich, Brian D. Berman, Marie Mailly, Emmanuel Roze, Marie Vidailhet, Joseph Jankovic, Mark S. LeDoux, Richard L. Barbano, Florence Chang, Victor Fung, Sarah Pirio Richardson, Andrew Blitzer, Hyder A. Jinnah

Journal Name: Frontiers in Neurology

Publisher: Frontiers Media SA

Vol: 12

Issue #:

Start Page:

End Page:

Publication Date: 2021-09-16

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.3389/fneur.2021.700714

Best OA location URL: https://www.frontiersin.org/articles/10.3389/fneur.2021.700714/pdf

Citation Count: 22

The intracellular milieu of Parkinson’s disease patient brain cells modulates alpha-synuclein protein aggregation

2021

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Title: The intracellular milieu of Parkinson’s disease patient brain cells modulates alpha-synuclein protein aggregation

Author(s): Nadja Gustavsson, Ekaterina Savchenko, Oxana Klementieva, Laurent Roybon

Journal Name: Acta Neuropathologica Communications

Publisher: Springer Science and Business Media LLC

Vol: 9

Issue #: 1

Start Page:

End Page:

Publication Date: 2021-09-16

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1186/s40478-021-01256-w

Best OA location URL: https://actaneurocomms.biomedcentral.com/track/pdf/10.1186/s40478-021-01256-w

Citation Count: 3

Dysregulation of mitochondrial and proteolysosomal genes in Parkinson’s disease myeloid cells

2021

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Title: Dysregulation of mitochondrial and proteolysosomal genes in Parkinson’s disease myeloid cells

Author(s): Elisa Navarro, Evan Udine, Kátia de Paiva Lopes, Madison Parks, Giulietta Riboldi, Brian M. Schilder, Jack Humphrey, Gijsje J. L. Snijders, Ricardo Assunção Vialle, Maojuan Zhuang, Tamjeed Sikder, Charalambos Argyrou, Amanda Allan, Michael J. Chao, Kurt Farrell, Brooklyn Henderson, Sarah Simon, Deborah Raymond, Sonya Elango, Roberto A. Ortega, Vicki Shanker, Matthew Swan, Carolyn W. Zhu, Ritesh A. Ramdhani, Ruth H. Walker, Winona Tse, Mary Sano, Ana C. Pereira, Tim Ahfeldt, Alison Goate, Susan Bressman, John F. Crary, Lotje De Witte, Steven J. Frucht, Rachel Saunders‐Pullman, Towfique Raj

Journal Name: Nature Aging

Publisher: Springer Science and Business Media LLC

Vol: 1

Issue #: 9

Start Page: 850

End Page: 863

Publication Date: 2021-09-14

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1038/s43587-021-00110-x

Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728893

Citation Count: 19

Effect of Urate-Elevating Inosine on Early Parkinson Disease Progression

2021

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Title: Effect of Urate-Elevating Inosine on Early Parkinson Disease Progression

Author(s): Brent Bluett, Daniel M. Togasaki, Dragos Mihaila, Marian L. Evatt, Michael Rezak, Samay Jain, Michael A. Schwarzschild, Alberto Ascherio, Cindy Casaceli, Gary C. Curhan, Rebecca Fitzgerald, Cornelia Kamp, Codrin Lungu, Eric A. Macklin, Kenneth Marek, Dariush Mozaffarian, David Oakes, Alice Rudolph, Ira Shoulson, Aleksandar Videnović, B.L. Scott, Lisa Gauger, Jason Aldred, Melissa Bixby, Jill Ciccarello, Steven A. Gunzler, Claire Henchcliffe, Matthew Brodsky, Kellie Keith, Robert A. Hauser, Christopher G. Goetz, Mark S. LeDoux, Vanessa K. Hinson, Rajeev Kumar, Alberto J. Espay, Joohi Jimenez-Shahed, Christine Hunter, Chadwick W. Christine, Aaron Daley, Maureen A. Leehey, Joy Antonelle de Marcaida, Joseph H. Friedman, Albert Y. Hung, Grace Bwala, Irene Litvan, David K. Simon, Tanya Simuni, Cynthia Poon, Mya Schiess, Kelvin L. Chou, Ariane Park, Danish Bhatti, Carolyn Peterson, Susan R. Criswell, Liana S. Rosenthal, Jennifer Durphy, Holly A. Shill, Shyamal H. Mehta, Anwar Ahmed, Andres Deik, John Y. Fang, Natividad P. Stover, Lin Zhang, Richard B. Dewey, Ashley Gerald, James T. Boyd, Emily Houston, Valerie Suski, Sherri Mosovsky, Leslie J. Cloud, Binit Shah, Marie Saint‐Hilaire, Raymond James, S. Elizabeth Zauber, Stephen G. Reich, David Shprecher, Rajesh Pahwa, April Langhammer, Kathrin LaFaver, Peter A. LeWitt, Patricia L. Kaminski, John L. Goudreau, Doozie Russell, David Houghton, Ashley LaRoche, Karen Thomas, Martha McGraw, Zoltan Mari, Carmen Serrano, Karen Blindauer, Marcie L. Rabin, Roger Kurlan, John C. Morgan, Michael J. Soileau, Melissa Ainslie, Iván Bódis-Wollner, Ruth Schneider, Cheryl Waters, Amber Servi Ratel, Christopher Beck, Patrick Bolger, Katherine F. Callahan, Grace F. Crotty, David Klements, Melissa Kostrzebski, Gearoid M. McMahon, Lindsay Pothier, Sushrut S. Waikar, Anthony E. Lang, Tiago Mestre

Journal Name: JAMA

Publisher: American Medical Association (AMA)

Vol: 326

Issue #: 10

Start Page: 926

End Page: 926

Publication Date: 2021-09-14

Open Access(OA) Status: RESTRICTED

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DOI - Digital Object Identifier: 10.1001/jama.2021.10207

Best OA location URL: https://jamanetwork.com/journals/jama/articlepdf/2784144/jama_schwarzschild_2021_oi_210070_1631212847.50479.pdf

Citation Count: 87

Peripheral and central immune system crosstalk in Alzheimer disease — a research prospectus

2021

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Title: Peripheral and central immune system crosstalk in Alzheimer disease — a research prospectus

Author(s): Brianne M. Bettcher, Malú G. Tansey, Guillaume Dorothée, Michael T. Heneka

Journal Name: Nature Reviews Neurology

Publisher: Springer Science and Business Media LLC

Vol: 17

Issue #: 11

Start Page: 689

End Page: 701

Publication Date: 2021-09-14

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1038/s41582-021-00549-x

Best OA location URL: https://www.nature.com/articles/s41582-021-00549-x.pdf

Citation Count: 164

Prescribing Aducanumab in the Face of Meager Efficacy and Real Risks

2021

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Title: Prescribing Aducanumab in the Face of Meager Efficacy and Real Risks

Author(s): David S. Knopman, Joel S. Perlmutter

Journal Name: Neurology

Publisher: Ovid Technologies (Wolters Kluwer Health)

Vol: 97

Issue #: 11

Start Page: 545

End Page: 547

Publication Date: 2021-09-14

Open Access(OA) Status: RESTRICTED

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DOI - Digital Object Identifier: 10.1212/wnl.0000000000012452

Best OA location URL: https://n.neurology.org/content/neurology/97/11/545.full.pdf

Citation Count: 25

Altered ceramide metabolism is a feature in the extracellular vesicle-mediated spread of alpha-synuclein in Lewy body disorders

2021

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Title: Altered ceramide metabolism is a feature in the extracellular vesicle-mediated spread of alpha-synuclein in Lewy body disorders

Author(s): Marzena Kurzawa‐Akanbi, Seshu R. Tammireddy, Ivo Fabrik, Lina Gliaudelytė, Mary K. Doherty, Rachel E. Heap, Irena Matečko‐Burmann, Björn M. Burmann, Matthias Trost, John M. Lucocq, Anda Gherman, Graham Fairfoul, Preeti Singh, Florence Burté, Alison Green, Ian McKeith, Anetta Härtlová, Phillip D. Whitfield, Christopher M. Morris

Journal Name: Acta Neuropathologica

Publisher: Springer Science and Business Media LLC

Vol: 142

Issue #: 6

Start Page: 961

End Page: 984

Publication Date: 2021-09-13

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1007/s00401-021-02367-3

Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00401-021-02367-3.pdf

Citation Count: 32

Rare variants in the endocytic pathway are associated with Alzheimer’s disease, its related phenotypes, and functional consequences

2021

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Title: Rare variants in the endocytic pathway are associated with Alzheimer’s disease, its related phenotypes, and functional consequences

Author(s): Lingyu Zhan, Jiajin Li, Brandon Jew, Jae Hoon Sul

Journal Name: PLOS Genetics

Publisher: Public Library of Science (PLoS)

Vol: 17

Issue #: 9

Start Page: e1009772

End Page: e1009772

Publication Date: 2021-09-13

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1371/journal.pgen.1009772

Best OA location URL: https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1009772&type=printable

Citation Count: 1

DUOGLOBE: One‐Year Outcomes in a Real‐World Study of Levodopa Carbidopa Intestinal Gel for Parkinson's Disease

2021

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Title: DUOGLOBE: One‐Year Outcomes in a Real‐World Study of Levodopa Carbidopa Intestinal Gel for Parkinson's Disease

Author(s): David G. Standaert, Jason Aldred, Marieta Anca‐Herschkovitsch, Paul Bourgeois, Esther Cubo, Thomas L. Davis, Robert Iansek, Norbert Kovács, Francesco E. Pontieri, Mustafa Siddiqui, Mihaela Simu, Lars Bergmann, Pavnit Kukreja, Weining Robieson, K. Ray Chaudhuri

Journal Name: Movement Disorders Clinical Practice

Publisher: Wiley

Vol: 8

Issue #: 7

Start Page: 1061

End Page: 1074

Publication Date: 2021-09-12

Open Access(OA) Status: RESTRICTED

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1002/mdc3.13239

Best OA location URL: https://doi.org/10.1002/mdc3.13239

Citation Count: 24