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Novel Small Molecules to Slow PD Progression in a Genetically Defined Subset of People with PD
… biology that afflicts patients when they present with symptoms decades after the pathologies started in the … novel drug discovery efforts. Hypothesis: We have started with human data and identified a target, with genetic and …
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Robert A. Pritzker Prize Winner’s ‘Serendipitous Discovery’ Leads to Improved Lives for Many with Parkinson’s
May 28, 2013
… Today, Deep Brain Stimulation (DBS) is the most commonly used surgical procedure to treat people with Parkinson’s disease (PD). For many, the difference …
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Drug With Potential to Slow or Stop Parkinson’s Moves into Next Phase of Clinical Testing
June 17, 2025
… prasinezumab announced this week that the drug is moving into the critical, Phase III stage of clinical trials. If … first disease-modifying medications for Parkinson’s to become available to the public. Prasinezumab targets a … maintain their quality of life for longer than they would without the drug? In the best-case scenario, the drug would …
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Podcast: Inosine May Hold Potential for Parkinson’s Disease, but Patients Urged to Act with Caution
December 23, 2013
… Today the Parkinson Study Group published in JAMA Neurology that with medical supervision, it is possible to safely raise … One quick, very important note: Inosine is available commercially as a dietary supplement, but patients should …
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Michael J. Fox Talks to 'The New York Times Magazine' on Staying Positive with Parkinson's
March 4, 2019
… Photo courtesy of "New York Times Magazine." Michael J. Fox sat down for an intimate interview with New York Times Magazine columnist David Marchese. In a series of …
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Contribution of the Unfolded Protein Response to Idiopathic and LRRK2-driven Parkinson’s Disease
… life-death switch that instructs aged and overworked cells to self-destruct. We hypothesize that hyper-activation of … brain tissue for markers of UPR activation from people with and without PD as well pre-clinical models of the … switch and test them in pre-clinical models. Anticipated Outcome: Based on preliminary work by ourselves and …