… health setbacks unrelated to his Parkinson’s diagnosis. From this moment in time emerged the key theme to his latest … when you keep coming back to gratitude, and what follows from that is acceptance. Accepting that this thing has …

… in alpha-synuclein PFF-induced pathology. Previous work from our group has shown that gene silencing of LRRK2 is … Demonstrating that LRRK2 silencing protects the brain from PD-like pathology in models will provide evidence in … Next Steps for Development: Successful protection from pathology in preclinical models is necessary to …

… disease and distinguishing Parkinson’s volunteers from control volunteers. No studies have been published on … fluid , frozen skin, and frozen submandibular gland samples from 35 cases of ILBD . We would compare positivity across … of previous findings. We will also test skin samples from an additional ~70 ILBD cases to add power to the study …

… synthesizing and labeling the leading AD tau-PET tracers from other laboratories, and preparing new chemical entities … These compounds are being evaluated in brain tissues from different tau-based disorders and from people with PD. Impact on Diagnosis/Treatment of …

… and healthcare access in Black people with PD could differ from that of their White counterparts, particularly in light … Black people with PD collected by a single medical center from 2006-2021. In combination with retrospective and …

… onset and progression of PD. Hypothesis:  Based on data from our earlier MJFF study, we hypothesize that two …  We will analyze both plasma and CSF samples collected from people with PD and from healthy volunteers using a technique called liquid …