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Finding Your Way: Working through Emotions in Early Years with Parkinson’s (Webinar Replay)
September 27, 2023
… and many other difficult emotions. This replay of audio from our Third Thursdays Webinar features a conversation … the early years following their diagnosis. We also hear from a psychologist who specializes in Parkinson’s on what … this podcast. Want to see the slides and other resources from the webinar? Watch on demand. Discover more …
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Targeting a Phospholipid Unique to Mitochondrial Membranes as a Therapeutic for Parkinson’s Disease
… PD models. Study Design: We will treat neurons derived from patient stem cells and a well-characterized preclinical … cellular energy production. We will analyze biofluids from the preclinical model and from patient-derived neurons to determine whether we can …
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Pharmacokinetics, Food Effects, Safety and Tolerability of Aggregation Inhibitor Anle138b in Parkinson´s Disease
… This grant builds upon the research from a prior grant: Anle138b Clinical Phase 1 Studies: Food … holds promise for slowing disease progression. Initial data from control volunteers who took anle138b capsules while … progression. Next Steps for Development: Based on the data from this trial, we will finalize the ongoing plans for …
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Target Validation Studies for the Discovery of Novel Small Molecule Therapeutics with the Potential to Modify Disease Outcome by Inhibiting Bacterial Amyloid Protein-induced Alpha-synuclein Aggregation and Associated Neuronal Toxicity
… treatments for their GI symptoms. Study Design: Nerves from the GI tract of mice that have been genetically … we will treat these cultures with novel molecules selected from our drug discovery program at Axial Biotherapeutics. … Development: The experimental tools and knowledge gained from this project complements the drug discovery program at …
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Development And Validation Of A Miro1 Biomarker Assay Using White Blood Cells
… AcureX will use established assays to translate findings from patient skin cells into an assay using patient white … we will validate the Miro1 assay using white blood cells from patients and matched healthy control subjects. Analytic … that slow PD disease progression will benefit significantly from having a clinical biomarker to monitor target …
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Jon Surine: 'I Don't Want to Be Defined by Parkinson's, I Want to Help Define It'
April 9, 2012
… 2012 issue of "Accelerating the Cure," we hear directly from PPMI participant Jon Surine. When I was first diagnosed … I wasn’t the first in his family to hear this news from my doctor — both my mother and father-in-law had PD — … by PD, I want to help define it. Jon Surine is now retired from a family-owned garden center in Texas Township, …