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Scientists Discover Potential Pathway of LRRK2 Dysfunction
April 14, 2014
… Researchers from Johns Hopkins University have reported on a potential … much of the PD research field, including many initiatives from The Michael J. Fox Foundation, is tuned to discover … goals, the Foundation is gathering data and biosamples from people with and without PD with a LRRK2 mutation …
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FOX FOTO FRIDAY: Start Your Engines
October 4, 2013
… Engineering Hospitality Tent was bustling with supporters from the Corvette Club of Connecticut, Whelen Engineering and race fans from all around the surrounding area. Also in attendance was … to all for coming out to cheer on Team Fox! To see more from the exciting day at Lime Rock Park, including footage …
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Getting Back in the Race with Team Fox
February 2, 2018
… made the decision to run the 2010 New York City Marathon from behind the barricades, cheering on a friend at the race in 2009. Sidelined for ten years from competitive racing due to challenges associated with … research! Christoph's ongoing commitment to Team Fox stems from MJFF's progress toward improving the lives of people …
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Nicole Jarvis's Oklahoma Winter Gala Snowballs into Success Year after Year
December 20, 2017
… $100,000. According to Nicole, "It kind of snowballed from there." Last year, the Winter Gala crossed the lifetime … has raised over $300,000 -- $100,000 coming in that evening from live and silent auctions -- for critical Parkinson's … Nicole appreciates the caring and support she experiences from the PD community and her own family the most. Says her …
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Neoangiogenesis and Blood-Brain Barrier in L-DOPA-induced Dyskinesia
… a process may modify the kinetics of levodopa transport from blood to brain in a way that favours the occurrence of … cancer. Additionally, she received supplemental funding from MJFF to test whether blocking new blood vessel … dyskinesias. She also examined post-mortem brain tissue from PD subjects to see if similar evidence of LDOPA-induced …
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Identification of LRRK2 Substrates in Pre-clinical Models of Parkinson's Disease
… phosphorylation by proteomic profiling of tissue from LRRK2 transgenic mice. We have generated transgenic … profile protein phosphorylation in brain tissue from young and aged LRRK2 transgenic mice compared with … tissue due to LRRK2 expression and/or familial mutations from various LRRK2 transgenic pre-clinical models and human …