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LRRK2 PET Tracer Development
… This grant builds upon the research from a prior grant: Development of LRRK2 Target Engagement … Outcomes of Original Grant: With our initial grant from MJFF, we focused on designing and synthesizing chemical … for determining the second endpoint. The deliverable from this work would be a LRRK2 PET ligand that would permit …
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Is Dysphagia in Parkinson’s Disease Caused by Lewy Pathology in the Upper Aerodigestive Tract?
… upper throat, larynx and esophagus lining tissue obtained from 10 subjects with clinically diagnosed and … PD will be studied. The autopsy subjects were derived from the Arizona Study of Aging and Neurodegenerative … six lining tissue samples (10x10 mm/each) will be obtained from the oropharynx (i.e., lateral posterior tongue, …
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Ira Shoulson, MD
… of Neurology at Georgetown University (Washington DC). From 2011 to July 2018, Dr. Shoulson was Professor of … Center of Excellence in Regulatory Science and Innovation. From 1990 to 2011, Dr. Shoulson was the Louis C. Lasagna … A. Pritzker Prize for Leadership in Parkinson's Research from The Michael J. Fox Foundation. Dr. Shoulson is an …
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"Smart" Studies: Digital Health Tools Help Understand the Daily Parkinson's Experience
May 20, 2019
… newsletter. For many, the experience of Parkinson's varies from day to day, hour to hour. That heterogeneity challenges … Some results are already coming in. An MJFF- funded study from Johns Hopkins University developed a Parkinson's severity score derived from smartphone assessments. Such a score could help direct …
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Anle138b Clinical Phase 1 Studies: Food Effect, Safety and Tolerability as well as Pharmacokinetics in Parkinson´s Disease Patients
… This grant builds upon the research from a prior grant: Evaluation of the Oligomer Modulator … to slow the progression of Parkinson’s. Initial data from healthy volunteers after intake of anle138b as a … Parkinson’s. Next Steps for Development: Based on the data from this trial, the team will finalize ongoing plans for …
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The New York Times Covers Environmental Factors in Parkinson’s Disease
July 23, 2020
… test flights. But at none of these jobs was he protected from exposure to hazardous chemicals that are readily … as the prevalence of PD worldwide is expected to double from 6 to 12 million by 2040. The MJFF public policy team … Register for our webinar on Thursday, August 20 from 12 to 1 p.m. ET. Kristina Magana Communications Officer …