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Development of Dopaminergic Cell Line Models of Alpha-synuclein Expression for High-throughput Drug Screenings and Monitoring of Alpha-synuclein Expression
… line is an induced pluripotent stem (iPS) cell line derived from PD patient skin cells that will produce a green … of Parkinson’s Disease: Cell lines generated resulting from this project will allow us to proceed to the next stage … PD patients. To start this project, we received funding from the Rapid Response Innovation Program to make cell …
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Analysis of a Viral Non-coding RNA as a Novel Therapeutic in a Chronic MPTP Pre-clinical Model of Parkinson's Disease and its Mechanism of Mitochondrial Protection
… model of PD, we have tested whether it protects rats from over-expression of alpha-synuclein. We have now shown … that this novel therapeutic can, indeed, protect animals from symptoms of PD due to the over-expression of alpha-synuclein and that this also occurs by protection from mitochondrial stress. …
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Study of a Molecule to Prevent Alpha-Synuclein Clumping and Treat Parkinson's Disease
… This grant builds upon the research from a prior grant: Utilization of Aptamers to Prevent … aptamer, which can bind to alpha-synuclein and prevent it from clumping. Aptamers are short strands of the cell's … aptamer, which can bind to alpha-synuclein and prevent it from clumping. Aptamers are short strands of the cell's …
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Parkinson's Doctors in Training Leading New Research Frontiers
May 13, 2019
… 2019, who are nearing graduation, recently shared learnings from studies they've led during their training on an … of patients with a LRRK2 mutation who had DBS with records from those who did not undergo surgery. She also looked at records from people with Parkinson's but without a LRRK2 mutation …
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Teaching Young Doctors about Parkinson's
March 28, 2019
… the latest research. In this year's course, 88 attendees from across North and South America learned from 12 world-renowned experts and six patients as well as … for Neurology Residents was made possible with support from the Edmond J. Safra Foundation and The Michael J. Fox …
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Choosing a Deep Brain Stimulation Device
… to determine which is the best one for you. DBS Devices from Abbott Abbott has two DBS devices : Infinity and … with Apple iOS software and controllers. DBS Devices from Boston Scientific Boston Scientific’s Vercise became … and lasts three to five years. DBS Devices from Medtronic Medtronic’s DBS was the first to be FDA …