The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Characterization of a Novel Strategy to Target LRRK2 and Its Downstream Signaling Pathway
Study Rationale: Genetic mutations that activate LRRK2 are linked to familial Parkinson’s disease (PD). However, no clinically approved inhibitors for LRRK2 currently exist. In this study, we will...
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Fall 2022 RFP: Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program - Biology, 2026Biomarker Discovery by Interrogating LRRK2 Signaling in Parkinson’s Biosamples with the Asian LRRK2 G2385R and R1628P Variants
Study Rationale:
Mutations in the LRRK2 gene are the most common genetic cause of Parkinson's disease (PD). Most research has focused on the LRRK2 G2019S mutation seen in Caucasians...
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Research Grant, 2026Biofluid Markers in Multiple System Atrophy
Study Rationale:
Multiple system atrophy (MSA) and Parkinson’s disease present with similar clinical symptoms, especially at early stages. Though both involve the abnormal accumulation of α-synuclein...
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Research Grant, 2026Parkinson’s Clinical Cohorts Collaborative (PC3)
Study Rationale:
Effective treatments for the symptoms of Parkinson’s exist, but none slow its progression. Inability to measure or predict future progression are major obstacles to...
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Research Grant, 2026Parallelized Digital Seed Amplification Assay for PD Biomarker Development
Study Rationale:
The amplification of small quantities of misfolded protein aggregates from clinical samples offers an attractive route towards developing sensitive diagnostics for a...
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Our funding programs support basic, translational and clinical research from academia and industry.