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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Parkinson’s Disease Therapeutics Pipeline Program, 2024
    Preclinical Development of a Novel Therapeutic for Parkinson’s Disease

    Study Rationale: Inflammation in the brain (neuroinflammation) is a key feature of Parkinson’s disease (PD), and signaling molecules called prostaglandins play a pivotal role in controlling chronic...

  • Research Grant, 2024
    (SUPPLEMENT) Cataloguing Proteomic Differences in LRRK2-Associated Parkinsonism With and Without Evidence of Pathologic Neuronal Alpha-synuclein

    Study Rationale: Alpha-synuclein is a protein found throughout the brain and body. In most people with Parkinson’s disease (PD), an accumulation of abnormal alpha-synuclein is thought to contribute to...

  • Biomarkers to Support Therapeutic Trials Program, 2024
    Using Detection of Apoptosing Retinal Cells to Predict Disease Activity in Parkinson’s Disease

    Study Rationale: In preclinical models, detection of apoptosing retinal cells (DARC) allows identification of cells in the eye that are under stress and at risk of damage from Parkinson’s disease (PD)...

  • Research Grant, 2024
    Developing A Resource for Exploring the Molecular Markers of Parkinson’s Disease

    Study Rationale: Our understanding of the genetic, immunological and molecular determinants of Parkinson’s disease (PD) has advanced significantly over the past decade. Using this extensive body of...

  • Research Grant, 2024
    Generation of Induced Pluripotent Stem Cells with Indigenous Ancestry to Promote Inclusion of North America’s First Peoples in Parkinson’s Disease Research

    Study Rationale: North America’s Indigenous people with Parkinson’s disease (PD) are largely underrepresented in research studies, and biological material from these populations is rarely available to...

  • Parkinson’s Disease Therapeutics Pipeline Program, 2024
    Discovery of Translational Pharmacodynamic Biomarkers and Biomarkers of Endo-lysosomal Pathway Pathology by Biased & Unbiased Lipidomics and Metabolomics

    Study Rationale: The endolysosomal system within living cells is comprised of small, specialized structures that contain enzymes that degrade proteins and remove waste materials from the cell. Their...

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Our funding programs support basic, translational and clinical research from academia and industry.

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