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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2024
    Developing an Open-access Repository of High-quality Digital Measurement Tools for Use in Parkinson’s Disease Research and Care

    Study Rationale: This study will bring together leaders in Parkinson’s disease (PD) and digital health innovation and measurement to develop and maintain an open-access repository of high-quality...

  • 2022: Accelerated Therapeutics Program, 2024
    (SUPPLEMENT) Small Molecule Mitochondrial Modulators for the Treatment of Parkinson's Disease

    Study Rationale: Mitochondrial dysfunction is a crucial driver of the initiation and progression of Parkinson’s disease (PD). Mitochondria are structures that produce cellular energy, and in neurons...

  • Parkinson’s Disease Therapeutics Pipeline Program, 2024
    Assessment of IRL757 for the Treatment of Apathy in Parkinson's Disease

    Study Rationale: People with Parkinson’s disease (PD) frequently develop a loss of motivation and initiative. Such apathy can be burdensome for patients and their families and caregivers and is...

  • Alpha-Synuclein Post-Translational Modifications Quantification Program, 2024
    Development of anAssay for Quantification of Alpha-synuclein and its Modifications

    Study Rationale: Many studies have shown that a protein called alpha-synuclein is abnormal in Parkinson's disease (PD), forming toxic aggregates that move through the brain and cause neuronal cell...

  • Research Grant, 2024
    Discovery of PET Tracers for Measuring Alpha-synuclein

    Study Rationale: The discovery of new treatments for Parkinson’s disease (PD) has been slowed by the amount of time (years) it takes to determine whether a drug was effective in a clinical trial. New...

  • 2022: Accelerated Therapeutics Program, 2024
    (SUPPLEMENT) Innovative Therapies for Parkinson’s Disease Through a Novel, Unexploited Gene Expression Mechanism Rooted in Human Genetics Enabling a Precision-medicine Approach

    Study Rationale: Parkinson’s disease (PD) and Alzheimer’s disease (AD) are neurodegenerative disorders caused by an accumulation of protein aggregates that leads to cell death. Genetic studies suggest...

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