Funded Studies

Study Rationale: The state of Hawai’i is ethnically diverse, with a mix of Southeast Asian, East Asian and North Americans, in addition to distinct indigenous Native Hawaiians and Pacific Islanders...

Study Rationale: In people with Parkinson’s disease (PD), chronic inflammation and metabolic reprogramming triggers neuronal cell death. Impaired function of the proteins involved in cellular...

Study Rationale:
The motor symptoms of Parkinson's disease (PD) result from the degeneration of the dopamine producing neurons in a brain area called the substantia nigra pars compacta (SNc). Recent...

Study Rationale:
Many people with Parkinson’s disease develop untreatable cognitive symptoms, including problems with attention, decision-making, and dementia at late stages of the disease, due to...

Study Rationale:
While neurodegeneration in Parkinson’s disease (PD) affects many cells, dopamine neurons are particularly vulnerable, and their loss drives many of the major motor difficulties in PD...

Study Rationale:
Nerve cells that produce the brain chemical dopamine die in people with Parkinson’s disease. These dopamine-producing nerve cells extend very long and thin fibers called axons that...