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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Priority Biology, 2021
    Efficacy of PRKN Gene Delivery toward Mitigation of Alpha-synuclein-induced Degeneration

    Study Rationale:
    Genetic mutations that cause the functional loss of the PRKN gene and its corresponding protein, parkin, can cause early-onset Parkinson’s disease (PD). Regardless of the cause...

  • Therapeutic Pipeline Program, 2021
    Understand Me for Life: An Intelligibility App for Parkinson's Disease

    Study Rationale:
    Approximately 90% of people with Parkinson’s develop speech and language problems over the course of the disease, and more than half of these speakers experience problems with...

  • Research Grant, 2021
    Parkinson’s Disease Patient Report of Problems (PD-PROP) Curation

    Study Rationale:
    What people with Parkinson’s feel and experience about their disease, and how it affects their lives, is of paramount importance to their care and participation in research. The...

  • Priority Biology, 2021
    Studying the Properties of Alpha-Synuclein Aggregates Amplified from Human Cerebrospinal Fluid

    Study Rationale:
    Aggregates of the protein alpha-synuclein, which accumulate in the brains of people with Parkinson’s disease (PD), can also be detected in biofluids like cerebrospinal fluid (CSF)...

  • Research Grant, 2021
    Hypoxia (Limiting Oxygen Levels) as a Novel Treatment for Parkinson’s Disease

    Study Rationale:
    Many anecdotes suggest that people with Parkinson’s disease (PD) can experience a marked improvement in symptoms when they travel to the mountains or during flights at high altitude...

  • Target Advancement Program, 2021
    SCARB2 as a Potential Target in Parkinson’s Disease

    Study Rationale:
    Mutations in GBA, a gene that encodes an enzyme called glucocerebrosidase, are a common risk factor for Parkinson’s disease (PD). Inside cells, glucocerebrosidase must be escorted to...

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