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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Sphingolipid and Alpha-synuclein Interactions

    Study Rationale:                   
    The contributions of multiple factors to Parkinson's disease (PD) are not fully understood.  However, it is clear that a normal cellular protein called alpha...


    Year Funded: 2019
  • Connexins as a New Therapeutic Target to Impede Spreading of Alpha-synuclein Pathology

    Study Rationale:
    Direct cellular connectivity has recently been implicated in the transfer of alpha-synuclein pathology associated with Parkinson’s disease. The gap junction proteins known as connexins...


    Year Funded: 2019
  • Biomaterial-enhanced Cellular Brain Repair for Parkinson's Disease

    Study Rationale:
    One promising approach for the treatment of Parkinson’s is to replace the cells that have died in the disease through transplantation of healthy cells into the brain. However, this...


    Year Funded: 2019
  • Study in Finnish Population to Identify Therapies with Repurposing Potential for Parkinson’s Disease

    Study Rationale:
    Effective treatments for slowing the progression of Parkinson’s disease are urgently needed. Searching for possible treatments among drugs already used for other indications is a...


    Year Funded: 2019
  • Astrocyte Activation as a Novel Marker of Disease Progression in Parkinson’s Disease: A PET Imaging Study

    Study Rationale:
    Brain inflammation, regulated by cells called microglia and astrocytes, has been shown to play a role in the initiation and progression of Parkinson’s disease. However, the role of...


    Year Funded: 2019
  • Analysis and Amplification of Pathological Alpha-synuclein from Brain Tissue

    Study Rationale:                   
    Parkinson’s disease is characterized by the misfolding and accumulation of the alpha-synuclein protein in the brain. Therefore, alpha-synuclein-based disease models...


    Year Funded: 2019
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