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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2018
    Registry for the Advancement of Deep Brain Stimulation Therapy in Parkinson's Disease

    Study Rationale:
    Deep brain stimulation (DBS) is a surgical therapy that delivers small electrical pulses to the brain to decrease movement symptoms of Parkinson's disease (PD). Registry for the...

  • Improved Biomarkers and Clinical Outcome Measures, 2018
    Developing a Test for Circular RNA, a Possible Biomarker of Parkinson's Disease

    Study Rationale:
    Circular RNA (circRNA) is a recently discovered type of RNA, a molecule that plays an important role in protein production. CircRNAs are abundant in the brain and builds up when...

  • Target Advancement Program, 2018
    Evaluating the Role and Therapeutic Potential of Natural Killer Cells in Parkinson's Disease

    Study Rationale:
    Natural killer (NK) cells are immune cells that defend the body against external and internal threats. While the number of NK cells is increased in Parkinson's disease (PD), it...

  • Research Grant, 2020
    Identification of Therapeutic Circuits to Address Anxiety and Depression Symptoms in Parkinson’s Disease

    Study Rationale: Parkinson’s disease patients often experience depression and anxiety. Addressing these non-motor symptoms has not been the focus of Parkinson’s disease research though psychiatric...

  • Astrocyte Biology in Parkinson's Disease, 2019
    Characterization of Astrocytes in Aging and Lewy Body Pathology

    Study Rationale:
    Astrocytes are brain cells with crucial roles, including communication between nerve cells, clearance of unwanted material, and response to injury. It has been suggested that...

  • Research Grant, 2019
    Long-acting GM-CSF Fusion Protein (PDM608) for the Treatment of Parkinson’s Disease

    Study Rationale:
    Emerging evidence suggests that the modulating the peripheral immune system can be a powerful disease-modifying approach for the treatment of Parkinson's disease (PD). We have...

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