The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2013Novel Quantification Paradigm in Parkinson’s Disease Neurochemical Imaging
Objective/Rationale:
Parkinson’s disease imaging using dopamine transporter (DAT) single-photon emission computed tomography (SPECT) technology conveys important information on brain... -
Rapid Response Innovation Awards, 2013Novel Method for Therapeutic Gene Silencing in the Brain
Objective/Rationale:
Reducing the activity of certain genes — called gene silencing — implicated in Parkinson’s disease may be a therapeutic approach that could prevent or slow the disease... -
Access to Data and Biospecimens, 2013Alpha-Galactosidase A and Glycosphingolipid Metabolites as Putative Biomarkers for Parkinson’s Disease
Objective/Rationale:
Alpha Galactosidase A (alpha-Gal A) is an enzyme that is ordinarily responsible for lipid recycling in cells. Researchers have shown how pre-clinical models that lack... -
Parkin Therapeutic Development, 2013Identification of Parkin Activators through Structure-Function Analyses
Objective/Rationale:
Mutations in the Parkin gene are the most common cause of recessive familial Parkinson’s disease. Additionally, the Parkin protein may also be inactivated in... -
Rapid Response Innovation Awards, 2013Determination of the 3D Structure of Biologically Active Small Molecules in Complex with DJ-1
Objective/Rationale:
Mutations in the DJ-1 gene have been associated with Parkinson’s disease onset. This project will determine the 3D structure of the DJ-1 protein in complex with novel... -
Target Validation, 2013Targeting the Voltage-Gated Proton Channel Hv1 for Neuroprotection
Objective/Rationale:
The goal of this project is to validate the voltage-gated proton channel Hv1 as a target to reduce neuroinflammation and subsequent neurodegeneration in acute and...
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Our funding programs support basic, translational and clinical research from academia and industry.