The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Community Fast Track, 2005Guidance of Midbrain Dopaminergic Neurons in Development and Disease
A promising approach to alleviating the symptoms of Parkinson's disease is to transplant healthy dopaminergic neurons into the brains of these patients. Due to the large number of dopaminergic neurons...
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Community Fast Track, 2005Specific Inhibition of Nucleation of Alpha-synuclein Aggregation As a Therapeutic Strategy
The pathological hallmark of Parkinson's disease is the accumulation in nerve cells of dense clumps of aggregated protein. The clumps, called Lewy bodies, contain mostly a protein called alpha...
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Community Fast Track, 2005K-ATP Channels and Their Role in the Survival of Nigral Dopaminergic Neurons
ATP-sensitive potassium (K-ATP) channels are present is numerous tissues including the brain. Their function has been best studied in the pancreatic B-islet cells that participate in the regulation of...
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Community Fast Track, 2005Use of NR2D-selective NMDA Receptor Modulators in the Treatment of PD
The frontline pharmacological treatment for Parkinson's disease is associated with serious side effects, creating a need for new therapeutic strategies. Recent evidence suggests that selective...
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Community Fast Track, 2005The role of serotonin neurons in the induction and maintenance of dyskinesias in grafted and L-DOPA-primed animals
Background: Levodopa, the most commonly used medication for patients with Parkinson's disease, is a beneficial therapy, but as the disease progresses it can be the cause of debilitating involuntary...
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LEAPS, 2005New Small Molecule Inhibiting Agents of Alpha-Synuclein & Lewy Body Formation as Disease-Modifying Treatments for Parkinson's Disease
Parkinson's Disease is pathologically characterized by the presence and accumulation of a protein known as alpha-synuclein. Mutations in alpha-synuclein have been directly linked to PD, and alpha...
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Our funding programs support basic, translational and clinical research from academia and industry.