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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Therapeutic Pipeline Program, 2020
    Novel Candidate against Alpha-synuclein for the Treatment of Parkinson’s Disease

    Study Rationale:
    The goal of this program is to develop a novel drug for Parkinson’s disease with a unique mechanism of action. We have a drug candidate that shows potential as an inhibitor of alpha...

  • Biosample Use Program, 2020
    Identification of Autoantibodies in People at Risk of Developing Parkinson’s Disease Using Microarrays

    Study Rationale:    
    Autoantibodies are antibodies that mistakenly target and react with a person's own tissues or organs. Autoantibodies can be detected many years before symptoms develop in many...

  • Research Grant, 2020
    GBA Variations, Cholinergic Degeneration, and Cognitive Decline in Parkinson’s Disease

    Study Rationale:
    Mutations in the GBA gene are the most common genetic risk factors for Parkinson’s disease. People with GBA mutations (GBA-PD) may develop the disease at a younger age and may have...

  • Research Grant, 2020
    Safety and Tolerability of NLX-112 in People with Parkinson’s

    Study Rationale:
    Motor symptoms of Parkinson’s disease are caused by a lack of brain neurons that carry a neurotransmitter called dopamine, and are commonly treated with levodopa. However, after...

  • Research Grant, 2020
    Parkinson’s Disease Subtyping by Genetic and Intestinal Inflammation Biomarkers

    Study Rationale: 
    Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide. Currently, no drugs are available to treat or prevent the disease because the processes...

  • Biosample Use Program, 2020
    Single-molecule Detection of Oligomeric Synuclein in Body Fluids

    Study Rationale:
    Clumps, or aggregates, of the protein alpha-synuclein have been detected in spinal fluid of people with Parkinson’s disease, where its concentration shows potential to be a biomarker...

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Our funding programs support basic, translational and clinical research from academia and industry.

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