To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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LRRK2 pT1357 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine1357 of LRRK2. Antibody is suitable for immunoblotting application after immunoprecipitating for LRRK2.
LRRK2 pT1410 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine1410 of LRRK2. Antibody is suitable for immunoblotting applications.
LRRK2 pT1491 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine1491 of LRRK2.
LRRK2 pT1503 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine1503 of LRRK2.
LRRK2 pT2483 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine 2483 of LRRK2.
LRRK2 R1441C Mouse*
Mouse Model
Transgenic mice expressing full length LRRK2 with R1441C mutation driven by CMV enhancer and PDGFB promoter/enhancer elements. Model was generated and deposited by Darren Moore at Van Andel Research Institute and Valina Dawson at Johns Hopkins University through the MJFF Sponsored Tools Program (available through cryorecovery). RRID:IMSR_JAX:016576
LRRK2 R1441G KI MEF
Immortalized Cell
Mouse embryonic fibroblast line with knockin of the LRRK2 R1441G mutation.
Expected availability: Late 2025
LRRK2 R1441G Mouse
Mouse Model
Transgenic mice overexpressing a mutant form (R1441G) of human LRRK2 directed by its endogenous promoter/enhancer regions on the BAC transgene. RRID:IMSR_JAX:018786
LRRK2 S910A/S935A Knockin Mouse*
Mouse Model
Mice carrying LRRK2 S910A and S935A mutations in exon 21. Model was generated and deposited by Dario Alessi at University of Dundee through the MJFF Sponsored Tools Program (available through cryorecovery). RRID:IMSR_JAX:028801
LRRK2 T1348N Mouse
Mouse Model
Mice expressing the T1348N mutant (GTPase-dead) form of LRRK2. RRID:IMSR_JAX:021829
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic